Beta-Lactamase DataBase
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Beta-Lactamase DataBase
Class A Sub-class B1 Sub-class B2 Sub-class B3 Class C Class D

Enzymes

Ambler sub-class B2 beta-lactamases
Sequence alignment for sub-class B2

Ambler
class
Protein
name
Alternative
protein names
Subfamily
GenPeptID
GenBankID
PubMedID (DOI)
Sequence
Number of PDB
structures
Mutants
Phenotype
Functional
information
Natural (N) or
Acquired (A)

CphA

Sequence alignment for CphA

Chromosomic β-lactamases found in Aeromonas species.

B2CphA-1CphA-1-likeCAA40386 X57102 1856163 (DOI) view113bN (Aeromonas hydrophila)
B2CphA-2A2hCphA-1-likeAAB03413 U60294 —(—)2327760 (DOI) viewN (Aeromonas hydrophila)
B2CphA-3CphA-1-likeAAP97130 AY261376 viewN (Aeromonas salmonicida)
B2CphA-4CphA-1-likeAAP69912 AY227050 viewN (Aeromonas allosaccharophila)
B2CphA-5CphA-1-likeAAP69913 AY227051 viewN (Aeromonas salmonicida)
B2CphA-6CphA-1-likeAAP69914 AY227052 viewN (Aeromonas veronii bv. veronii)
B2CphA-7CphA-1-likeAAP69915 AY227053 viewN (Aeromonas jandaei)
B2CphA-8CphA-1-likeAAP97129 AY261375 viewN (Aeromonas sobria)
B2CphA-9CphA-1-likeAAP97131 AY261377 viewN (Aeromonas veronii)
B2CphA-10CphA-1-likeAAP97133 AY261379 viewN (Aeromonas hydrophila subsp. hydrophila)
B2CphA-11ImiSCphA-1-likeCAA71441 Y10415 9527802 (DOI) viewN (Aeromonas veronii)
B2CphA-12CphA-1-likeAKI85140 KP771880 25987617 (DOI) viewN (Aeromonas hydrophila AQAH5)
B2CphA-13ImiHCphA-1-likeCAD69003 AJ548797 12746371 (DOI) viewN (Aeromonas hydrophila)
B2CphA-14CphA-1-likeWP_082186785 NZ_KV861289 viewN (Aeromonas sobria)
B2CphA-15CphA-1-likeWP_082035432 NZ_CDBV01000017 viewN (Aeromonas jandaei)
B2CphA-16CphA-1-likeAAM63403 AY112998 viewN (Aeromonas veronii bv. sobria)
B2CphA-17CphA-1-likeAAP97132 AY261378 viewN (Aeromonas veronii bv. veronii)

CVI

B2CVI-1WP_164461288 NG_067986 37513808 (DOI) viewN (Chromobacterium violaceum)

PFM

Sequence alignment for PFM

Chromosomally-located β-lactamases found in Pseudomonas species, probably acquired.

B2PFM-1QDC33502 MN065826 31685461 (DOI) viewN (Pseudomonas fluorescens)
B2PFM-2KRP45299 JYLH01000007 31685461 (DOI) viewN (Pseudomonas libanensis DSM 17149)
B2PFM-3QGJ02507 MN080497 31685461 (DOI) viewN (Pseudomonas fluorescens PF-1)
B2PFM-4BioFOAE14554 LVWZ01000046 34725905 (DOI) viewN (Pseudomonas brenneri RGCB 108)

SFH

B2SFH-1WP_024531368 NZ_AUZV01000091 12821491 (DOI) view5CarbapenemaseN (Serratia fonticola)

YEM

B2YEM-1CQH06348 CTIO01000005 32540974 (DOI) viewCarbapenemaseN (Yersinia mollaretii 107/02)

* after the protein name denotes a temporary name in BLDB, while waiting for a definitive assignment by NCBI.
GeneBankIDs represented in bold face correspond to entries for which NCBI has assigned a RefSeq.

Statistics (number of entries): Overall (8432); class A (2015); subclass B1 (621); subclass B2 (24); subclass B3 (309); class C (3958); class D (1308).

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)