Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-63-like beta-lactamase family

OXA-63
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.........
MSKKNFILIFIFVILISCKNTEKISNETTLIDNIFTNSNAEGTLVIYNLNDDKYIIHNKERAEQRFYPASTFKIYNSLIGLNEKAVKDVDEVFYKLMA-KSFLESWAKDSNLRYAIKNSQVPAYKELARRIGIKKMKENIEKLDFGNKSIGDSVDTFWLEGPLEISAMEQVKLLTKLAQNELQYPIEIQKAISDITITRANLHITLHGKTGLADSKNMTTEPIGWFVGWLEENDNIYVFALNIDNINSDDLAKRINIVKESLKALNLLK
OXA-136 ...............................................................................................YNGE.V...............................L.................................................P........V.....LEQTYNY.................................................................  94.42 %
OXA-137 ...............T...............................................................................YNGE.V...............................L.....................................I...........P........V.....LEQTYNY.................................................................  93.68 %
OXA-192 .......................T.......................................................................YNGE.V...............................LE..............N.................................P........V.....LEQTDNY...........E.........L.......N...................................  92.19 %
OXA-470 ...............................................................................................YNGE.V...............................L.....................................I...........P........V.....LEQTYNY.....................................................E...........  93.68 %
OXA-471 ...............................................................................................YNGE.V...............................L.................................................P..............LEQTYNY.................................................................  94.80 %
OXA-472 ...............................................................L...Q...........................YNGE.V...............................L.....................................I...........P........V.....LEQTYNY...........................-.....................................  92.94 %
OXA-473 ...............................................................................................YNGE.V...F...........................L.................................................P..............LEQTYNY.................................................................  94.42 %
OXA-474 .................................V.............................................................YNGE.V...F...........................L.................................................P........V.....LEQTYNY.................................................................  93.68 %
OXA-475 ...............................................................................................YNGE.V...............................L.................................................P........V.....LEQTYNY...........E............................................G........  93.68 %
OXA-476 ...............................................................................................YNGE.V...............................L...................N.............................P........V.....LEQTYNY...........E.....................................................  93.68 %
OXA-477 .................................V.............................................................YIGE.V...F...........................L...............N......................E..........P........V.....LEQTYNY.................................................................  92.94 %
OXA-478 ...............................................................L...............................YNGE.V..........S....................L........................GI.......................P........V.....LEQTYNY........V........................................................  92.57 %
OXA-479 ...............................................................................................YNGE.V...............................L.....................................I...........P........V.....LEQTYNY.................................................................  94.05 %
OXA-1099 ...............................................................................................YNGE.V...............................L............................L....................P..............LEQTYNY.................................................................  94.42 %
OXA-1100 ......................................................V........................................YNGE.V...............................L.....................................I...........P........V.....LEQTYNY.................................................................  93.68 %
OXA-1101 ............I.......................................................................V..........YNGE.V...............................L.................................................P........V.....LEQTYNY.................................................................  93.68 %
OXA-1102 .Y..IS...L.............T.D.............T.......D..EN.............................Y.............YNGE.V...............................LE..............N...C.............................P......E.V.....LEQTDNY.F.........D....N............N...........V.....E...S.......S.....  85.87 %
OXA-1103 .Y..IS...L.............T.D.............T.......D..EN.............................Y.............YNGE.V.....V.........................LE..............N.................................P......E.V.....LEQTDNY.F.........D.I..N............N...........V.....E...S.......S.....  85.50 %
OXA-1104 .Y..IS...L.............T.D.............T.......D..EN.............................Y.............YNGE.V.....V.........................LE..............N.................................P......E.V.....LEQ.DNY...........E....N............N...I.......V.....E...S.......S.....  86.25 %
OXA-1105 .Y..IS...L.............T.D.............T.......D..EN.............................Y.............YNGE.V...............................LE..............N.................................P......E.V.....LEQ.DNY...........E....N............N...I.......V.....E...S.......S.....  86.62 %
OXA-1106 .Y..IS...L.............T.D.............T.......D..EN............I................Y.............YNGE.V.....V.........................LE..............N.................................P......E.V.....LEQTDNY.F.........D....N............N...........V.....E...S.......S.....  85.50 %
OXA-1107 .Y..IS...L.............T.D.............T.......D..EN.............................Y.............YNGE.V...............................LE..............N.................................P......E.V.....LEQTDNY.F.........D.I..N............N...........V.....E...S.......S.....  85.87 %
D-OXA-63-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)