Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
Beta-Lactamase DataBase - Structure and Function Home Enzymes Structures Mutants Kinetics BLAST
Beta-Lactamase DataBase

Sequence alignment for the OXA-61-like beta-lactamase family

OXA-61
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280......
------------------MKKITLFLLFLNLVFGQDKILNNWFKEYNTSGTFVFYDGKTWASNDFSRAMETFSPASTFKIFNALIALDSGVIKTKKEIFYHYRGEKVFLSSWAQDMNLSSAIKYSNVLAFKEVARRIGIKTMQEYLNKLHYGNAKISKIDTFWLDNSLKISAKEQAILLFRLSQNSLPFSQEAMNSVKEMIYLKNMENLELFGKTGFNDGQKIAWIVGFVYLKDENKYKAFALNLDIDKFEDLYKREKILEKYLDELVKKVKNDG-----------
OXA-193 ------------------.........................................................................................................................................................................................................E.......................................................-----------  99.61 %
OXA-450 ------------------.................................................T.......................................................................................................................................................E.......................................................-----------  99.22 %
OXA-451 ------------------...................................................................V.....................................................................................................................................E.......................................................-----------  99.22 %
OXA-452 ------------------.............................I...........................................................................................................................................................................E.......................................................-----------  99.22 %
OXA-453 ------------------......................................................................................G..................................................................................................................E.......................................................-----------  99.22 %
OXA-460 ------------------...................................................................................................................T.....................................................................................E..................................................S---------------  97.28 %
OXA-461 ------------------...............................................L.........................................................................................................................................................E..................................................S---------------  97.28 %
OXA-489 ------------------................................................................................................................................D........................................................................E.......................................................-----------  99.22 %
OXA-577 ------------------...................................................................................................................T.....................................................................................E.......................................................-----------  99.22 %
OXA-578 ------------------..............................................................................................V..........................................................................................................E.......................................................-----------  99.22 %
OXA-579 ------------------.......................................................................C.................................................................................................................................E.......................................................-----------  99.22 %
OXA-580 ------------------........................................................T................................................................................................................................................E.......................................................-----------  99.22 %
OXA-581 ------------------.......................................................................................................................................................................R.................................E.......................................................-----------  99.22 %
OXA-582 ------------------.......................................................................................................................................................................I.................................E.......................................................-----------  99.22 %
OXA-583 ------------------..................................................................................................................................................................K......................................E.......................................................-----------  99.22 %
OXA-584 ------------------.........................................................................................................................................................................................................E.........................N.............................-----------  99.22 %
OXA-585 ------------------.........................................................................................................................................................................................................E...T...................................................-----------  99.22 %
OXA-586 ------------------.....................................................................................................................................D...................................................................E.......................................................-----------  99.22 %
OXA-587 ------------------.....................................................................................................................................................P...................................................E.......................................................-----------  99.22 %
OXA-588 ------------------................................................................T........................................................................................................................................E.......................................................-----------  99.22 %
OXA-589 ------------------.....................................................................................................................................................................................I...................E.......................................................-----------  99.22 %
OXA-590 ------------------..............................R..........................................................................................................................................................................E.......................................................-----------  99.22 %
OXA-591 ------------------.......................................................................................................................................................................................C.................E.......................................................-----------  99.22 %
OXA-592 ------------------...................V.....................................................................................................................................................................................E.......................................................-----------  99.22 %
OXA-593 ------------------...................................................................................................................V............D........................................................................E.......................................................-----------  98.83 %
OXA-594 ------------------.........................................................................................................................................................T...............................................E.......................................................-----------  99.22 %
OXA-595 ------------------.........................................................................................................................................................V...............................................E.......................................................-----------  99.22 %
OXA-596 ------------------.................................................T.....................................................................................................................................C.................E.......................................................-----------  98.83 %
OXA-597 ------------------...................V.............................................................................I.......................................................................................................E.......................................................-----------  98.83 %
OXA-598 ------------------..........................................................................................................................................................................-..............................E.......................................................-----------  99.22 %
OXA-599 ------------------................................................................................................................................D.............................T..........................................E.......................................................-----------  98.83 %
OXA-600 ------------------....................................................................................T............................................................................................................................................................................-----------  99.61 %
OXA-601 ------------------.........................................................................................................................................................V...............................................E..................................................S---------------  97.28 %
OXA-602 ------------------...............................................................................................................................................................................I.........................E..................................................S---------------  97.28 %
OXA-603 ------------------.........................................................................................................................................................................................................E...................V..............................S---------------  97.28 %
OXA-604 ------------------......................................................................................G........................................................................................I.........................E..................................................S---------------  96.89 %
OXA-605 ------------------...................................................................................................................T.....................................................................................E..................................................KLKMMASEYFVKCKNT  93.28 %
OXA-606 ------------------.........................................................................................................................................................................................................E...................V..............................KYLIV-----------  97.28 %
OXA-607 ------------------.............-----.......................................................................................................................................................................................E.......................................................-----------  97.67 %
OXA-608 ------------------.........................................................................................................................................................................................................E...................T...................................-----------  99.22 %
OXA-609 ------------------.........................................................................................................................................................................................................E......................................................D-----------  99.22 %
OXA-610 ------------------.........................................................................................................................................................................................................E......................................................S-----------  99.22 %
OXA-611 ------------------..........................................V..............................................................................................................................................................E.......................................................-----------  99.22 %
OXA-612 ------------------..........................................G..............................................................................................................................................................E.......................................................-----------  99.22 %
OXA-659 MQPKSIILFFYGYILFFRRQ.....................................................................................................................................................................................C.................E.......................................................-----------  92.00 %
OXA-660 ------------------.......................................................................................................................................................................................C.................E.................................C.NT-----------------------------  91.05 %
OXA-784 ------------------.................................................T.............................................................................................................................I.........................E.......................................................-----------  98.83 %
OXA-786 ------------------.........................................................................................................................................................................................................E......................................NFR.IFR---------------------  93.39 %
D-OXA-61-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)