Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-60-like beta-lactamase family

OXA-60
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.
MLSRYSKTLAFAVVACTLAISTATAHAELVVRNDLKRVFDDAGVSGTFVLMDITADRTYVVDPARAARSIHPASTFKIPNSLIAFDTGAVRDDQEVLPYGGKPQPYEQWEHDMALPEAIRLSAVPIYQEVARRVGFERMQAYVDAFDYGNRQLGSAIDQFWLRGPLEISAFEEARFTSRMALKQLPVKPRTWDMVQRMLLIEQQGDAALYAKTGVATEYQPEIGWWAGWVERAGHVYAFALNIDMPREGDMAKRIPLGKQLMRALEVWPAP
OXA-444 .F..W..P.VL.ATV.AM.M.A.......I..........E............S..............R........................H............K............................L...................V..............L........................H..............................V.......R...........................Q..D...VL  89.67 %
OXA-570 .FA.W...F.L.LT..AFVMGATQ.....I..D.......E...T........SGN............R........................H..I........FK...K.........V.N..........I.PA.....M.........I..V.......................L.............L.H...M..R....S..................V.....E.K...........L.A......L...R..Q..D...T.  80.81 %
OXA-571 .F..W..PFVL.ATV.AM.M.A.......I..........E............S..............R........................H............K............................L...................V.......................................H..............................V.......R...........................Q........  90.77 %
OXA-573 .FP.W...F.L.LT.YAFVMGASQ........D.......E...T........RG.............R...........................I........FK...K.........V.N..........I.PA...............I..V.......................L.............L.H......K.......................V.....E.K...........L.A..........R..Q......T.  83.39 %
OXA-898 ...CC..SF...LM..L..T.A...R..............A............S..............R........................H...........FK...............................................GV..............L........................H..............................V.......R...........................Q......TL  90.77 %
OXA-1176 .F..W..PFVL.ATV.AM.M.A.......I..........E............S..............RM.......................H............K............................L...................V.......................................H.......................R......V.......R...........................Q........  90.04 %
D-OXA-60-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)