Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-50-like beta-lactamase family

OXA-50
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260...
MRPLLFSALL-LLSGHTQASEWNDSQAVDKLFGAAGVKGTFVLYDVQRQRYVGHDRERAETRFVPASTYKVANSLIGLSTGAVRSADEVLPYGGKPQRFKAWEHDMSLRDAIKASNVPVYQELARRIGLERMRANVSRLGYGNAEIGQVVDNFWLVGPLKISAMEQTRFLLRLAQGELPFPAPVQSTVRAMTLLESGPGWELHGKTGWCFDCTPELGWWVGWVKRNERLYGFALNIDMPGGEADIGKRVELGKASLKALGILP
OXA-395 ..........-.....A..................................................................K...................................................................................................................................................................................  99.24 %
OXA-396 .....L....-..................................................................................................E.........................................................H...............................................................................................  98.85 %
OXA-485 ..........-....RA........................................................................................................................H.............................................................................................................................  98.85 %
OXA-486 ..........-......................................C...........................................................E.........................................................................................................................................................  99.24 %
OXA-488 ..........-.....A........R.............................................................................................................................................................................................................................................  99.24 %
OXA-494 ..........-..................................................................................................E.........................................................H...............................................................................................  99.24 %
OXA-846 ..........-.....A...............................................................................................E......................................................................................................................................................  99.24 %
OXA-847 ..........-......................................C...........................................................E.........................................................H...............................................................................................  98.85 %
OXA-848 ..........-.....A........R.........................................................K...................................................................................................................................................................................  98.85 %
OXA-849 .....I....-.....A...............................................................................................E......................................................................................................................................................  98.85 %
OXA-850 ..........-............................................................................................................................................................H...............................................................................................  99.62 %
OXA-851 ..........-.....A......................................................................................................................................................................................................................................................  99.62 %
OXA-901 ..........-.....A......N.R.............................................................................................................................................................................................................................................  98.85 %
OXA-902 ....F.....L.F...A.......................................G..........................K...................................................................................................................................................................................  97.72 %
OXA-903 ..........-......................................C.....................S.....................................E.........................................................................................................................................................  98.85 %
OXA-904 ..........-..................................................................................................E.........................................................................................................................................................  99.62 %
OXA-905 ..........-.....A...................................................................................................................................A..................................................................................................................  99.24 %
OXA-906 ..........-.....A........H...............................................................................................................H.............................................................................................................................  98.85 %
OXA-907 ..........-.....A..............................................................I...K...................................................................................................................................................................................  98.85 %
OXA-908 ..........-.....A..................................................................K................................................H...............A..................................................................................................................  98.47 %
OXA-913 ..........-.....A........R.........................................................................N...................................................................................................................................................................  98.85 %
OXA-914 ..........-................................................................................................................................S...........................................................................................................................  99.62 %
OXA-937 ..........-...............................................................................................................................................................I............................................................................................  99.62 %
OXA-1014 ..........-.....A..................................................................K.........................E........................D................................................................................................................................  98.47 %
OXA-1018 ..........-..F.........................................................................................................................................................................................................................................................  99.62 %
OXA-1019 ..........-.........................................................................................V...........E...................................................................................................................................T..................  98.85 %
OXA-1020 ..........-......................................C...........................................................E...................................................................................................................................................V.....  98.85 %
OXA-1021 ....F.....L.F...A.......................................G..........................K............................................................................................................................................................................T......  97.34 %
OXA-1022 ..........-.....A..................................................................K............................E....................................................................................Q.................................................................  98.47 %
OXA-1023 ..........-.....A...........................N......................................K................................................H................................................V.................................................................................  98.09 %
OXA-1024 ..........-.....A..................................................................K............................E............................................................................T.........................................................................  98.47 %
OXA-1025 ..........-..................................................................................................E.........................................................H............................S..................................................................  98.85 %
OXA-1026 ..........-.....A........R...................................................................................E.................................................N.......H...............................................................................................  98.09 %
OXA-1027 ..........-.....A............................................................................................E.........................................................................................................................................................  99.24 %
OXA-1028 ..........-......................................C...........................................................E............................................................I............................................................................................  98.85 %
OXA-1029 ..........-....P................................................................................................E...................................................................................................................................T..................  98.85 %
OXA-1030 ..........-..............R.............................................................................................................................................................................................................................................  99.62 %
OXA-1031 ..........-.....A.............................................................................................................................................................................................................................S........................  99.24 %
OXA-1032 ..........-.....A..................................................................K............................E......................................................................................................................................................  98.85 %
OXA-1033 .....L....-.....................................................................................................E.........................................................I............................................................................................  98.85 %
OXA-1034 .....L....-............................................................................................................................................................................................................................................................  99.62 %
OXA-1035 .......T..-.....A...............................................................................................E......................................................................................................................................................  98.85 %
OXA-1124 ..........-.....A.....................................................M............K...................................................................................................................................................................................  98.85 %
OXA-1125 ..........-......................................C.....................................................................................................................................................................................................................  99.62 %
OXA-1126 ..........-.............................................................................G....................E.........................................................H...............................................................................................  98.85 %
OXA-1127 ..........-.....A................................L.....................................................................................................................................................................................................................  99.24 %
OXA-1128 ..........-........................................A...................................................................................................................................................................................................................  99.62 %
OXA-1129 ..........-.....................................................................................................E..........................S.....................................................................................Y..................T..................  98.47 %
OXA-1130 .....L....-..................................................................................................E.........................................................................................................................................................  99.24 %
OXA-1131 ..........-.....A............................................................................................E.........................................................H...............................................................................................  98.85 %
OXA-1132 ..........-.....................................................................................................E..............................T....................................................................................................T..................  98.85 %
OXA-1133 ..........-.....................................................................................................E..........................S........................................................................................................T..................  98.85 %
OXA-1134 ..........-...E.................................................................................................E..............................T....................................................................................................T..................  98.47 %
OXA-1135 ..........-.....................................................................................................E...................................................................................................................................T..................  99.24 %
OXA-1140 ..........-......................................C...........................................................E................................................M........................................................................................................  98.85 %
OXA-1174 ..........-.....A...............................................................................................E............................................................................T.........................................................................  98.85 %
OXA-1188 ..........-.....A..........................H.......................................K...................................................................................................................................................................................  98.85 %
OXA-1198 ..........-.....A................................................................................H.....................................................................................................................................................................  99.24 %
OXA-1199 .....L....-.............................................................................................................................................................L..............................................................................................  99.24 %
D-OXA-50-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)