Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
Beta-Lactamase DataBase - Structure and Function Home Enzymes Structures Mutants Kinetics BLAST
Beta-Lactamase DataBase

Sequence alignment for the OXA-48-like beta-lactamase family

OXA-48
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.....
MRVLALSAVFLVASIIGMPAVAKEWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP
OXA-54 .........LV....V....M.N....KP...T..S...A...I...........................................................A.....D.....................Q....................L................VA.............................S................Q.........................A.....................  92.45 %
OXA-162 ....................................................................................................................................................................................................................A....................................................  99.62 %
OXA-163 ..................................................................................................................................................................................................................--YD--T................................................  97.36 %
OXA-181 .......................................................................................................A.....D.........................................................Q..A..............................................................................................  98.49 %
OXA-199 .....................................Y......A............................................................................................................G...............................................................................................................  98.87 %
OXA-204 .................................................................................................HR......................................................................................................................................................................  99.25 %
OXA-232 .......................................................................................................A.....D.........................................................Q..A..........................................S...................................................  98.11 %
OXA-244 .....................................................................................................................................................................................................................G...................................................  99.62 %
OXA-245 ............................................................................................................................Y............................................................................................................................................  99.62 %
OXA-247 ..................................................................................................................................................................................................................--SN--T................................................  97.36 %
OXA-252 ............................................A............................................................................................................................................................................................................................  99.62 %
OXA-370 ...................................................................................................................................................................................................................E.....................................................  99.62 %
OXA-405 ..................................................................................................................................................................................................................--YS--.................................................  97.74 %
OXA-416 ........................................................................................................................................................L.T.............................................A................................................................  98.87 %
OXA-436 ..A......LM.TTM....................S...T..........T......D.............................................A.....D..........................................L..............Q..A.............................A...........V............I..........T......AE......T...A.........  91.32 %
OXA-438 ...................................................................................................................................................................................................................GYD--T................................................  97.74 %
OXA-439 ..........................................................................................................................H.......................................................................................--YD--T................................................  96.98 %
OXA-484 .......................................................................................................A.....D.........................................................Q..A..........................................G...................................................  98.11 %
OXA-505 .......T.................................................................................................................................................................................................................................................................  99.62 %
OXA-514 ........................................................................................................................................................L.T..............................................................................................................  99.25 %
OXA-515 ............................................A...........................................................................................................................................................S................................................................  99.25 %
OXA-517 .....................................................................................................................................................................................................................K--.................................................  98.87 %
OXA-519 .......................................................................................................................L.................................................................................................................................................  99.62 %
OXA-535 ..A......LM.TTM....................S...T..........T......D.............................................A.....D..............G...........................L..............Q..A.............................A...........V.......................T......AE......S...A.........  91.32 %
OXA-538 ........................................................................................................................................................................................................A...........G.....F..............................................  98.87 %
OXA-546 ............................................A.........................................................................................................................I..................................................................................................  99.25 %
OXA-547 ......................R.........V.....................................................................................................................................I..................................................................................................  98.87 %
OXA-566 ............................................................................................................................................D............................................................................................................................  99.62 %
OXA-567 ...................................................................................................................................................................................................................D.K.-G................................................  98.49 %
OXA-731 ..A......L..........E....K.TQ...T......T..............Y..D.............................................A.....D..................K..Q...N................L.............IQ..E.............................A...........V.......................T..............T.............  91.32 %
OXA-788 .......................................................................................................................L..........................................................................................--YD--T................................................  96.98 %
OXA-793 ......................................................................................................................................................................................................................--.................................................  99.25 %
OXA-833 .......................................................................................................A.....D.........................................................Q..A..........................................S............................................T......  97.74 %
OXA-894 ......................................................................................................................................................................I..................................................................................................  99.62 %
OXA-918 ..........................................................................T..............................................................................................................................................................................................  99.62 %
OXA-920 ........................................................................................................................................................................................................................S................................................  99.62 %
OXA-922 .......................................................................................................A.....D........................................................IQ..A..........................................G...................................................  97.74 %
OXA-923 .................................Y.....................................................................A.....D.........................................................Q..A..............................................................................................  98.11 %
OXA-924 .......................................................................................................A.....D.........................................................Q..A..........................................E...................................................  98.11 %
OXA-929 ..................................................................................................................................................................................................................--YS--A................................................  97.36 %
OXA-933 ..............................................................................................................................................................N..........................................................................................................  99.62 %
OXA-934 .................................Y.......................................................................................................................................................................................................................................  99.62 %
OXA-1012 .....................................................................................................................................................................................................................---S................................................  98.49 %
OXA-1038 ..........................................................................................................................................................T...........I..................................................................................................  99.25 %
OXA-1039 ..........................................................................................................................................................................T..............................................................................................  99.62 %
OXA-1055 ......................................................................................................................................................................................................................--S................................................  98.87 %
OXA-1119 .......................................................................................................A.....D.........................................................Q..A.........................................I....................................................  98.11 %
OXA-1146 .....................................................................................................................................................................................................................E--.................................................  98.87 %
OXA-1167 .....................................................................................................................................................................................................................S...................................................  99.62 %
OXA-1181 .......................................................................................................A.....D.........................................................Q..A........................................................................W.....................  98.11 %
OXA-1200 ..................................................................................................................................................................................................................--YS--TR...............................................  96.98 %
OXA-1201 .....................S.................................................................................A.....D.........................................................Q..A..........................................S...................................................  97.74 %
OXA-1205 .......................................................................................................A.....D.........................................................Q..A..........................................S.............................W.....................  97.74 %
OXA-1207 .......................................................................................................A.....D.........................................................Q..A..........................................G.............................W.....................  97.74 %
OXA-1211 .......................................................................................................A.....D.........................................................Q..A........................................L.....................................................  98.11 %
OXA-1212 .........................................................................................................................................................................................................................N...............................................  99.62 %
OXA-1213 ................E....................................................................................................................................................................................................G...................................................  99.25 %
OXA-1226 .......................................................................................................A.....D........................................................IQ..A..............................................................................................  98.11 %
OXA-1240 ..................................................................................................................................................................................................................--YG--T................................................  97.36 %
D-OXA-48-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)