Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-46-like beta-lactamase family

OXA-46
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260......
MAIRFFTILLSTFFLTSFVYAQEHVVIRSDWKKFFSDLQAEGAIVIADERQAKHTLSVFDQERAAKRYSPASTFKIPHTLFALDADAVRDEFQVFRWDGVNRSFAGHNQDQDLRSAMRNSTVWVYELFAKDIGEDKARRYLKQIDYGNVDPSTIKGDYWIDGNLKISAHEQILFLRKLYRNQLPFKVEHQRLVKDLMITEAGRSWILRAKTGWEGRFGWWVGWIEWPTGPVFFALNIDTPNRTDDLFKREAIARAILRSIDALPPN
OXA-118 .....L.............H.....LE...........R.......S.....E.A.L..G...............L........................K...................A.........E..K....H.........A...............E.......S............Q.................N...................V..........................................  91.73 %
OXA-119 .....L.............H.....LE...........R.......S.....E.A.L..G...............L........................K...................A.........E.................A...............E.......S............Q.................N...................V..........................................  92.48 %
OXA-205 .....L.............H......V.........................E.A.L..G...............L.........G..............K...................A.........E....N............A.......N.......E.......S............Q........Y........N................I..V..........................................  91.73 %
OXA-779 .............................................................................................................N............................................................................................................................................................  99.62 %
OXA-835 ....I.A...................................................................................................................................................................................................................................................................  99.25 %
D-OXA-46-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)