Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-294-like beta-lactamase family

OXA-294
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.....
-------MSKKLKLLALCATVISAATLVGCQNIQSQAQPLVLKKQAQDQIATAFENIQTTGVLVTYDGKNFQRYGNDLSRADQRYIPASTFKMLNALIGIQHHKTSPNEVFKWDGQKRAFRSWEQDLTLAEAMQASAVPVYQELARRIGLELMASEVKRVGYGNQNIGTQFDNFWLVGPLEITPVEEVKFAYALAKQQLPFAPSTQQQVRDMLLIENVQGTRIYAKSGWGMDVNPQVGWWTGWVEQPNGQITAFSLNMEMKKAEHADARKAIVYQALQQLGLLPQ
OXA-295 -------......................................T..........................K...................................................K......G....................................A.V..............................D.........................................I..T......................................  96.76 %
OXA-297 MLFNFIV.P......V.SVV.MPSII.L......PHV.T..TQ..TE............S.........AI.K...A.N..N....................................V.T...K........................................S....V.........................K..A.DS......K......DI...K...........K................V............A..E..................  82.46 %
OXA-298 MLFNFIV.P........SVV.MPSII.L......PHV.A..TQ..TE............S.........AI.K...A.N.........................................T...K........................................S....V.........................K..A.DS......K......DI...K...........K................V............A..E..................  83.51 %
OXA-982 -------............A.........................T..........................K...................................................K.............................................V..............................D.........................................I......V.....................I............  96.76 %
OXA-984 -------.P......V.SVV.MPSII.L......PHV.A..TQ..TE............S.........TI.T...A.N.........................................T...K........................................S....V.........................K..A.DS......K......DI...K............................V............A..E...............IG.  84.89 %
OXA-993 -------......................................T.......................K..K...................................................K.............................................V..............................D....................................R...........V..................................  97.12 %
OXA-994 -------......................................T..........................K...................................................K......G....................................A.V..............................D............................I............I.........................................  96.76 %
OXA-995 -------.P......F..IAAMPSI..L......PHV.T.AAQ..TE............S.........AI.T...A.N..N......................................T...K............................T...........S....V.........................E..A.DS......K......DI...K............................V............A..E...............IR.  84.17 %
OXA-996 -------.P........SVV.MPSII.L......PHV.T..AQ..TE............S.........AI.K...A.N.........................................T...K........................................S....V.........................K..A.DS......K......DI...K............................V............A..E..................  85.97 %
OXA-997 -------.................................A...............................K...................................................K......G....................................P.V..............................D...................................................................................  97.48 %
OXA-998 -------.P......V.SVV.MPSII.L......PHV.T..TQ..TE............S.........AI.K...A.N..N......................................T...K...........................I............S....V.........................K..A.DS......K......DI...KL...........................V............A..E..................  84.53 %
OXA-1004 -------.P......F.SVV.MPSI..L......QHV.T..AQ..TE............S.........AI.K...A.N..N...............................N......T...K........................................S....V.........................K..A.DS......K......DI...K............................V............A..E...............IR.  84.53 %
D-OXA-294-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)