Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-286-like beta-lactamase family

OXA-286
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270..........
MIMSKKLTCLALFTAIFFAIPMAACQSFSQQKQQLSTQKNEQQQISSLFQSAQTSGVLVIYDGKKIQSYGNDLDRAEQRYIPASTFKMLNALIGIQHHKTTPDEVFKWDGKKRAFSSWEKDLTLAEAMQASAVPVYQELARRIGLELMTREVKRVGYGNKNIGTQVDNFWLVGPLKITPVEEVRFAYALAKQKLPFDQPTQQQVKAMLLVDQIQGTKIYAKSGWGMDVSPQVGWWTGWIEQPNGKITAFSLNMQMSQPEHADARKAIVYQALQQLGLLAH
OXA-287 --.....K.......V......T...........F.......................M........................................................................................................................I.....................................................................................V.......E......  96.43 %
OXA-288 .M.....K...F..........T.................................................................................M.............................................................................................S......G...I.EV............................A...........E..R....E.............D...N  94.29 %
OXA-291 --.....KM.T.SISMMLGL.LM...........IM..ER.....T....N................KF...VH..D.........................K.......Q.......................................................................................S......G.....EVH...........................A...........E..R...TE.............D...N  85.71 %
OXA-292 --.....KM.T.SISMMLGL.LM...........IM..ES.....A....N................KF...VH..D.........................K.......Q.......................................................................................S......G...I.EV............................A...V.......E..R....E.............D...N  85.71 %
OXA-293 --..A..KI.T.SISLVLGL.LM...........IM...S.....A....N................K....TS...H........................N.I.....R......................................Q.I.......N.V....................................S......G...L.EV..A.........................A...........E.......ET............D..VN  83.93 %
OXA-302 .M.....K....L.PCILILQLT....V..........T...............K..................N.............I........Y.....N..........T........S....................................................Q.........V............S......G...A.ER................................TI..............N...V.......E.....N  87.86 %
OXA-303 .M.....K...F..........T...............................N............KF..............................................................................................................I.....................................................................................V.......E......  96.43 %
OXA-306 --...R.KT...SASFT..L.LV.....GD.T.HIMA..S...N.AT...Q................K....TS............................N.......Q.......................................................................................S......G...I.EV...............N............A...V.......E.NR..................D...N  84.64 %
OXA-307 --.....K....L.PLILIL.LT....P..K...VVSLQ....RVAN...Q...T.........Q..T...ATR..D..F.......I..............N.......Q...........S.....................................H........................V............S......D.....EH...............T.................I...........A......V.......E.....N  82.86 %
OXA-670 --.....K....L.PLILIL.LT....S..K...VVSL-....RVAN...Q...I.........Q..T...ATR..D..F.......I..............N.......Q...........S..............................................................V............S......G.....EH...............T.................I..................V.......E.....N  83.57 %
OXA-671 .......K..T................L.......T.E..D..............................A............................A.N...............................................................................................................D..............................VI................................T  95.36 %
OXA-672 .......K..T.............................................................IH..D...........................................................................................................................................................................................................  98.21 %
OXA-673 .......................................................................................................................................................................T..................................................................L..............................V..............  98.93 %
OXA-674 .M.....K...F..........T.................................................VH..........................................................................S............................................................................................................................E......  97.14 %
OXA-1145 ......................T...N........M....................................IH..D...........................L...............................................................................................................................................................................  97.50 %
OXA-1215 ......................................................R...M....................................................................................................................................................................................A........................................  98.93 %
D-OXA-286-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)