Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-243-like beta-lactamase family

OXA-243
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.....
MTVRLSSTALGAALSLSALAGAPAQAAVLCTVVADAADGRIVYQQGTQQACAARYTPASTFKLPIALMGADAGILTGPHAPVWNYQPGYPDWGGDAWRQPTDPARWIKYSVVWYSQLTARALGQERFQRYASAFHYGNEDVSGEPGKHNGLDGAWINSSLRISPLEQLAFLRKLVNRQLPLKAAAYDLAENLFEVGEAGGWHLYGKTGTGSPGSNGVYTAANAYGWFVGWARKDGRQLVFARLVQDEQATKPNAGLRARDDLMRDWPAMADAPRK
OXA-364 .PL..PLR........F.......S.................F.....A...E......................Q.A........................................................Q...............................................P.......T..DA......R.................PD......................L...K..R.........E.L.E.........Q  90.18 %
OXA-455 ....RF.C................R.................F.....A...E......................Q..........................................................Q...............................................P.......T..DA......R...........G.....PD......................L...K..R.......................Q  92.36 %
OXA-457 .....F.....................I........................................................................................................................................................V.................S............................................................................  98.55 %
OXA-458 .........................................................................................................................................................................................................RMH.......................................................................  98.91 %
OXA-459 .......C...............................................................................D..............................................................T.....I................V......V....................R.H.......................................................................  97.09 %
OXA-513 ....RF.C.............V..R.................F.....A...E......................Q..........................................................Q...............................................P.......T..DA......R.................PD......................L...K..........................Q  92.73 %
OXA-787 .PL..PLR........F.......R.................F.....A...E......................Q..........................................................Q...............................................P.......T..DA......R.................PD......................L...K..R.........K.L.E.........Q  90.55 %
OXA-789 .PL..PLR........F.......R.................F.....A...E......................Q..........................................................Q...............................................P.......T..DA......R.................PD......................L...K..R.........E.L.E.........Q  90.55 %
D-OXA-243-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)