Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-23-like beta-lactamase family

OXA-23
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270....
MNKYFTCYVVASLFLSGCTVQHNLINETPSQIVQGHNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPASTFKMLNALIGLENQKTDINEIFKWKGEKRSFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQVDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMDIK-PQVGWLTGWVEQPDGKIVAFALNMEMRSEMPASIRNELLMKSLKQLNII
OXA-27 ..............................................................................................A.................................................................................................................................-......................K..........................  99.27 %
OXA-49 ...................................................................................................................................................E........................................................................AMDIK.................................................  97.81 %
OXA-73 ................................................................................................................................................................................................................................-......................K..........................  99.63 %
OXA-103 ...................................................................................................................................................E..D...............I.....................................................-MDIK.................................................  97.08 %
OXA-105 .........F......................A...............................................................................................................................................................................................-..A..............................................  98.90 %
OXA-133 ..............F.............Q..................................................................................T...................................E..D...............I........................................N............-MDIK.................................................  95.62 %
OXA-146 ............................................................................................................................................................................................................................AMDIK.................................................  98.18 %
OXA-165 ..............................................................................................................................................................................................................................V.-.................................................  99.63 %
OXA-166 ...................................................A............................................................................................................................................................................-.................................................  99.63 %
OXA-167 ................................................................................................................................................................................................................................-......................................M..........  99.63 %
OXA-168 ................................................................................................................................................................................................................................-......A..........................................  99.63 %
OXA-169 ..............................................R.................................................................................................................................................................................-.................................................  99.63 %
OXA-170 ..............................................................................................................................................................................................................K.................-.................................................  99.63 %
OXA-171 ................................................................................................................................................................................................................................-.................................T...............  99.63 %
OXA-225 ................................................................................................................................................................................................................................-S................................................  99.63 %
OXA-239 ............................................................................................................L................................................................................................................N..-S................................................  98.90 %
OXA-366 ...................A............................................................................................................................................................................................................-.................................................  99.63 %
OXA-398 ................................................................................................................................................................................................................................-Q................................................  99.63 %
OXA-422 ............P...................................................................................................................................................................................................................-.................................................  99.63 %
OXA-423 ...............................................................................................................................A................................................................................................-.................................................  99.63 %
OXA-435 ................................................................................................................................................................................................................................-......S..........................................  99.63 %
OXA-440 ..............................................................................................................................................................................................................................K.-.................................................  99.63 %
OXA-481 ................................................................................................................................................................................................................................-........................................N....----  98.17 %
OXA-482 ........................................N.......................................................................................................................................................................................-.................................................  99.63 %
OXA-483 ................................................................................................................................................................................................................................-...................V.............................  99.63 %
OXA-565 ..........................K.Q...........................A...................................................................................................................................................................-MDIK..................T..............................  96.72 %
OXA-657 .............................................................................................................................................................................................................................G..-.................................................  99.63 %
OXA-806 ..........................K.Q...........................A...................................................................................................................................................................-MDIK............................G....................  96.72 %
OXA-807 ..........................K.Q...........................A......................................................G............................................................................................................-MDIK..................T..............................  96.35 %
OXA-808 ............................Q...........................A......................................................G............................................................................................................-MDIK..................T...............L..............  96.35 %
OXA-809 ......Y..F................DAQ.................................................................................I....................................E..D...T.................................................................-MDIK.................................................  94.89 %
OXA-810 ...............................................................................................................................................................................................................N................-.................................................  99.63 %
OXA-811 .........F......................................................................................................................................................................................................................-............................G....................  99.27 %
OXA-812 ............................Q.E...............................................................................I....................................E..D...T.................................................................-MDIK.................................................  95.99 %
OXA-813 .........F......................A...............................................................................................................................................................................................-.................................................  99.27 %
OXA-814 ............................Q...........................A......................................................G............................................................................................................-MDIK..................T..............................  96.72 %
OXA-815 ............................Q......................................................................................................................E..D...............I........................................N............-MDIK.................................................  96.35 %
OXA-816 ............................Q.................................................................................I....................................E..D...T.................................................................-MDIK.................................................  96.35 %
OXA-817 ............................Q..................................................................................T...................................E..D...............I........................................N............-MDIK.................................................  95.99 %
OXA-818 ............................Q...........................A......................................................G............................................................................................................-MDIK.................................................  97.08 %
OXA-911 ................................................................................................................................................................................................................................K.................................................  99.64 %
OXA-966 ............................Q......................................................................................................................E..D...T.................................................................-MDIK.................................................  96.72 %
OXA-967 ............................Q......................................................................................................................E..D...............I.....................................................-MDIK.................................................  96.72 %
OXA-968 .........F.....................................S.....................................................................I.............................E..D...............I.....................................................-MDIK..........................Q.G....................  95.26 %
OXA-969 ............................Q.....................................................I........K...................T..........I........................E..D...............I....................................................V-MDIK................V.........Q......................  94.16 %
OXA-1095 .............................................................T..............................................................................................................................................................AMDIK.................................................  97.81 %
OXA-1216 ..............................K...V.....N.......................................................................................................................................................................................-.................................................  98.90 %
OXA-1223 ...F............................................................................................................................................................................................................................-.................................................  99.63 %
D-OXA-23-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)