Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-22-like beta-lactamase family

OXA-22
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.........
-MKRRHAAIGALLAALATFAHAEHPICTIVADAATGKAVLHEGKCDERVTPASTFKLALAVMGFDHGFLKDEHTPVEHFRHGDPDWGGEAWHQPIDPALWLKYSVVWYSQRITHAMGAQTFQAYVRKLGYGNMDVSGDPGKNNGMDRSWITSSLKISPEEQVGLMRRIVNRQLPVSAHTYEMLDRTVQTWQVPGGWAVQGKTGTAGPAPGNTSPDGTWDQAHAYGWFVGWARKG----DKTYVFANLIQDDKVEPTSGGIRSRDALFARLSEVLAFAGH
OXA-443 MT.L...TT..F.............V..L........V..Q....N.................Y.A.....P........R.......RP.R..V..T.....................M.AS.....D...............L..................FL..L.........Q....V..............................A.................K..----GR............I............ML...PQ...A.KP  84.73 %
OXA-569 M..L....T..............RT............V.....Q.A.................Y.........A.I..MKA................T......................LH..L..FD.....A.........L..................F..K...............VE.A....P.....T..........G.......................K..TGDDSR............L......L......L...P....L.S.  84.59 %
OXA-572 M..L....T..F................L........V.VQ....N.................Y.A.....P........R.......QP.R..V..T.......................AS.....D...............L..................FL..L.........Q....V..I...........................A.................K..----GQ............I............ML...AQ...A.KP  85.45 %
OXA-574 M..L....T..............RT............V.....Q.A.................Y.....R.....I..MKA................T......................LH..L..FD.....A.........L..................F..K...............V.......P................G.......................K..TGDDSR............L......L......L...P....L.S.  85.66 %
OXA-899 M.......T.......................G.......Q..R.......................................................................................................................F.............R....V.............S.H...................................----............................L...P.......Q  95.27 %
OXA-1177 M..L....T..F................L........V.VQ....N.................Y.A.....P........R.......QP.R..V..T.......................AS.....D.........L.....L..................FL..L.T.......Q....V..I...........................A.................K..----GQ............I............ML...AQ...A.KP  84.73 %
D-OXA-22-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)