Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-213-like beta-lactamase family

OXA-213
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270...
MYKKALIVATSILFLSACSSNMVKQHQIHSISANKNSEEIKSLFDQAQTTGVLVIKRGQTEEIYGNDFKRASTDYVPASTFKMLNALIGLEHHKATTTEVFKWNGQKRLFPDWEKDMTLGDAMKASAIPVYQELARRIGLDLMSKEVKRVGFGNANIGSKVDNFWLVGPLKITPQQETQFAYQLAHKTLPFSKDVQEQVQSMVFIEEKNGSKIYAKSGWGWDVEPQVGWLTGWVVQPQGEIVAFSLNLEMKKGTPSSIRKEIAYKGLEQLGIL
OXA-267 .......A.............T...........................M.................L.....A.............................D.............................................I............D...............L.............Q...........................................S....................................  95.97 %
OXA-268 ........T............S........M...........................K........L.....A.I...........................D................N............................I...........................................................................................................................  96.34 %
OXA-269 ....V.....TT........KT............Q................................L..S..E........I...........V........D...................Q........K......................D...R..............L..AE...E..........N.......L........R........AL.ID................................I.....T..........  89.38 %
OXA-304 ....V.V..IAT.........T.............................................I.....E.............................D.............................................I.....D..................E.......E..N.......N................R..........................................I.................V.  93.41 %
OXA-305 ....V.V...AT.........T................................V............L.....E.........................I...D..................................R....T.....I.....D..................E.......K..N.......N................R..........................................I.................V.  92.31 %
OXA-322 ....V................S.............................................L.....N.I...........................D.............................................I............D.............................Q................................................................................  96.70 %
OXA-323 .....................T...N.........................................L.....A......................I......D.............................................I..........................................Q................................................................................  97.07 %
OXA-324 ....T...T............S........M...........................K........L.....A......................A......D.............................................I........................................................................................................................A..  95.97 %
OXA-325 .....................T.......T.....................................L.......I...........................D.............................................I............D..............................N................R..............................................................  96.70 %
OXA-326 .....F...............T................A............................L..........................V........D.............................................I............D..............................N...............................................................................  96.70 %
OXA-327 .....................T.............................................L.....A...........................................................................I..........................................Q..............................................................................V.  97.80 %
OXA-328 ...........L.........T.T..................................K........L.....A.............................D................N..............Q.............I...........................................N...............................................................................  95.97 %
OXA-329 .....................T................A............................L.....A.....................I.......D.............................................I............D........................M......................R...........I..................................................  95.97 %
OXA-330 .....................L.............S...............................L.....A...........................................................................I...........................................N............K...............................................S..................  97.07 %
OXA-331 .....................T...N.........................................L.....A......................I......................S.............................I............D..............................N...............................................................................  96.70 %
OXA-332 .....................T.............................................L.....A.............................D.............................................I...........................................................................................................................  98.17 %
OXA-348 ...................................................................L...................................................S.............................I............D..............................N...............................................................................  98.17 %
OXA-349 .......A........S....T.............................................L...P.A.............................D...................................................S.............................L......Q........................................I.......................................  95.97 %
OXA-350 ........T............S...N.........................................L.....A.............................D.............................................I............D..............................N........................................................N......................  96.34 %
OXA-351 .........I.........................................................L...................................................S.............................I............D..............................N...............................................................................  97.80 %
OXA-352 .....................T.............................................L.......I...........................D.............................................I............D..............................N................R...........I..................................................  96.70 %
OXA-353 ....T...T.....................M...........................K........L.....A.......................................K...................................I............D..............................N............K...............................................S..................  95.60 %
OXA-354 .....................S.............................................L...................................D.............................................I............D........................M......................R...........I..................................................  97.07 %
OXA-357 .......A........S....T.............................................L..........................V........D.............................................I.....D................S.E.......K..N.......N.............................................................................V.  94.87 %
OXA-358 .....................T.............................................L.....A.............................D........................................Q...............................................Q............................................................I...................  97.44 %
OXA-359 .....F.....L.........T.E....Y......................................L.....E.....I................A......D.............................................I...........................A................................R.......................I......................................  94.87 %
OXA-417 .T....FF.IGTM......F.T.Q....Q...T.....K..........E.................L..S..E......................P......D........................................N....I.....D......D..............A....E..........N........L.......R............................K.............I...................  89.01 %
OXA-522 .T....FF.IGTM......F.T.Q....Q...T.....K..........E.................L..S..E......................P......D.............................................I.....D......D.............KA....E..........N........L.......R............................K.............I...................  89.01 %
OXA-526 .T....FF.I.TM......F.T.Q....Q...T.....K..........E.........I..V....P............................P......D.............................................I.....D......D..............A....E..........N........L.......R..........................................I...................  90.11 %
OXA-805 ....V.V...AT.........T.............K..................V............L.....E.........................I...D.............................................I.....D..................E.......K..N.......N................R..........................................I.................V.  92.67 %
OXA-819 .T....FF.I.TI......F.T.Q.....A..TH................................NL.....E.........................M...D................E............................I.....D..........................E..........N..........V.....R..............................................................  91.21 %
OXA-822 ....V................T.E....Y............................E.K.......L.....E......................A......D................N............................I...........................A................................RR.............................................................  94.51 %
OXA-844 ...........L.........T.E....Y..A......K....................K.......V.....E......................A......D........................................Q....I..................................................T.........R..............................................................  94.51 %
OXA-979 .I.Q..FF.I.TI......F.T.Q.Q...A..TH........................N........L.....E.............................D.............................................I.....D.....................A...DE..........N..........V.....R..............................................................  90.48 %
OXA-980 .T....FF.IGTM......F.T.E....QL..T.....K..........E.........I..V....L.....E.F....................P......D.............................................I.....D.....................V....K..........N........L.......R..................F...I.......I...........I...................  87.91 %
OXA-985 .S....FF.I.TI......F.T.Q.....A..TH...........R.....................L.....E......................P......D................E............................I.....D.....................A....E..........N..........V.....R............D..........I......................................  90.11 %
OXA-987 ....V.V...AT.........T...................Y.........................L.....A.............................D.............................................I...................................L......Q.........................................I..................I.................V.  94.51 %
OXA-989 .I.Q..FF.I.TI......F.T.Q.Q...A..TH........................N........L.....E.............................D.............................................I.....D......D..................DE..........N..........V.....R..............................................................  90.48 %
OXA-990 .......A........S....T...........................M.......E.........L.....A.............................D...................................................S.............................L.......N............................................................A..................  95.60 %
OXA-1003 ....V.V...AT.........T.......A.................Y...................L.....E.............................D.......................................A.....I.....D..................E.......E..N.......N........M.......R..........................................I.................V.  92.31 %
OXA-1007 ....V.V...AT.........T...............Q.........H...............F...L.....E.......................A.....DR......................................A.....I.....D..................E.......E..N.......N................R..........................................I.................V.  91.58 %
OXA-1008 .T....FF.I.TI......F.T.Q.....A..TH........................N........L.....E.............V...............D.............................................I.....D.....................A....E..YT......N..........V.....R..............................................................  90.48 %
OXA-1009 .......A........S....T.............................................L.....A.............................D........................................................................................Q................................................................................  97.44 %
OXA-1010 .T....FL.I.TI......F.T.Q.....A..TD........................K........L.....E.......................I.....D.............................................I.....D.....................A....E..........N..........V.....R.L........................................I...................  90.48 %
OXA-1050 ....V................T.E....Y............................E.K.......L.....E......................A......D................N............................I...........................A................................RR...........K.................................................  94.14 %
OXA-1137 .T...FFF.I.TI......F.T.QH....A..TH........................N........L.....E.............................D.............................................I.....D.....................A....E..........N..........V.....R..............................................................  90.84 %
OXA-1151 ....V................T................A............................L.....S.............................D........................................................................................Q.................T...........I..................................................  96.70 %
OXA-1185 .....................T..................R..........................L.....A.............................D.............................................I.....D..................E.......K..N.......N...............................................................................  95.97 %
OXA-1189 ......FF.IGTV.......HT.E.P.T.F.P.........................EKA..V....L.....E.............................D.............................................I........................E..A...............N........M.......N.........L............................................S.......  89.74 %
OXA-1224 .T....FF.IGTM......F.T.Q....Q...T.....K..........P............V....L.T...E......................P......D.............................................I.....D......D..............A....E..........N........L.......R..........................................I...................  89.38 %
D-OXA-213-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)