Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-2-like beta-lactamase family

OXA-2
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270......
MAIRIFAILFSIFSLATFAHAQEGTLERSDWRKFFSEFQAKGTIVVADERQADRAMLVFDPVRSKKRYSPASTFKIPHTLFALDAGAVRDEFQIFRWDGVNRGFAGHNQDQDLRSAMRNSTVWVYELFAKEIGDDKARRYLKKIDYGNADP-STSNGDYWIEGSLAISAQEQIAFLRKLYRNELPFRVEHQRLVKDLMIVEAGRNWILRAKTGWEGRMGWWVGWVEWPTGSVFFALNIDTPNRMDDLFKREAIVRAILRSIEALPPNPAVNSDAAR
OXA-3 ...........T.VFG........MR.........................T..VI....Q...E......................A.....V.....IK.S..A.................I.........E........Q.......-P.........D.N...A............H....................................I............P.............................................  89.86 %
OXA-15 .....................................................................................................................................................G.-............................................................................................................................  99.64 %
OXA-21 ...........T.VFG........MR.........................T..VI....Q...E......................A.....V.....IK.S..A.................I.........E........Q.......-P.........D.N...A............H.................................................P.............................................  90.22 %
OXA-32 .......................................................................................................................................................-............I...............................................................................................................  99.64 %
OXA-53 ...Q.......T.V........D........G....D................H.I....QA..M...................................K.S.....K.........................G.......Q.G.....-P...H........................Q.D.................................S.............P......................A....L...........H.....  90.22 %
OXA-141 .......................................................................................................................................................-..........S.................................................................................................................  99.64 %
OXA-161 ...................................................................................................................................................D...-............................................................................................................................  99.64 %
OXA-210 .......................................................................................................................................................-......C.....................................................................................................................  99.64 %
OXA-226 .......................................................................................................................................................-.......R....................................................................................................................  99.64 %
OXA-415 .......................................................................................................................................................-..........D.................................................................................................................  99.64 %
OXA-539 ......................................................................................................................................................DP............................................................................................................................  99.28 %
OXA-540 ..........................A............................................................................................................................-............................................................................................................................  99.64 %
OXA-541 ...................................................................................................................................................Y...-............................................................................................................................  99.64 %
OXA-543 .......................................................................................................................................................-.......G....................................................................................................................  99.64 %
OXA-544 ............................................................................L..........................................................................-............................................................................................................................  99.64 %
OXA-681 ......................................................................................................................................................-P........K-..................................................................................................................  98.55 %
OXA-737 ....................................................................................................................................................P..-............................................................................................................................  99.64 %
OXA-838 ...................................................................................................................................................K...-............................................................................................................................  99.64 %
OXA-1017 ....................................................................................................................I..................................-..............................................................K.............................................................  99.27 %
OXA-1049 .....................................................................................................................................................Y.-............................................................................................................................  99.64 %
OXA-1082 .......................................................................................................................................................-..........C.................................................................................................................  99.64 %
OXA-1083 ....................................................................................................................I..................................-..............................................................................P.............................................  99.27 %
OXA-1084 ......................................................................................................................................................S-L...........................................................................................................................  99.27 %
OXA-1085 ......................................................................................................................................................-P......C----.................................................................................................................  97.46 %
OXA-1136 ...........T.VFG........MR.........................T..VI....Q...E......................A.....V.....IK.S..A.................I.........E........Q......G-P.........D.N...A............H.................................................P.............................................  89.86 %
OXA-1172 .....................................................................................................................................................-DP...........-I...............................................................................................................  98.19 %
OXA-1173 ....................................................................................................K.S.....K.........................G.......Q.G.....-P...H........................Q.D.................................S.............P......................A....L...........H.....  94.20 %
OXA-1183 .....................................................................................................................................................V.-............................................................................................................................  99.64 %
OXA-1187 ......................................................................................................................................................-P.......LE-..................................................................................................................  98.19 %
OXA-P99 .......................................................................................................................................................-.......C..................................................................................................------------------  93.09 %
D-OXA-2-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)