Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the OXA-12-like beta-lactamase family

OXA-12
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260....
MSRLLLSGLLATGLLCAVPASAASGCFLYADGNGQTLSSEGDCSSQLPPASTFKIPLALMGYDSGFLVNEEHPALPYKPSYDGWLPAWRETTTPRRWETYSVVWFSQQITEWLGMERFQQYVDRFDYGNRDLSGNPGKHDGLTQAWLSSSLAISPEEQARFLGKMVSGKLPVSAQTLQYTANILKVSEVEGWQIHGKTGMGYPKKLDGSLNRDQQIGWFVGWASKPGKQLIFVHTVVQKPGKQFASIKAKEEVLAALPAQLKKL
OXA-724 ..........GA...FSL.....T...........A................................D.......F..G..D........................................................................Q................................SD......................E.................................L............K..T.  93.18 %
OXA-725 .......S.......A.L..................................................D.......F..G..D.........................................................................................................ID........................................................L............K..T.  95.45 %
OXA-726 ..........GA...FSL.....T............................................D.......F..G..D.................................................................A......Q................................ID........................................................L............K..T.  93.56 %
OXA-912 .......S...A...A.L...............................................Y..D................................................................................................L......................ID........................................................L................Q  95.83 %
OXA-950 ..........GA...FSL.....T............................................D.......F..G..D.................................................................A......Q................................ID......................E.................................L............K..T.  93.18 %
OXA-951 ..........GA...FSL.....T............................................D.......F..G..D................................D.......................................Q................................ID........................................................L............K..T.  93.56 %
OXA-958 .......S...A...T.L..................................................D.......F..G..D.........................................................................................................ID...................................L....................L.................  95.45 %
OXA-959 .......S...A...A.L..................................................D.......F..G..D.........................................................................................................ID........................................................L...........GK..T.  94.70 %
OXA-1157 .......S...A...A.L.............................Q.................Y..D................................................................................................L..............T.....N.ID........................................L...............L...........GK..T.  93.56 %
OXA-1162 .......S...A...A.L...............................................Y..D................................................................................................L......................ID.........................................................................Q  96.21 %
D-OXA-12-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)