Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the SRT-SST-like beta-lactamase family
SRT-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370........
MTKMNRLAAALIAALILPTAQAAQQQDIDAVIQPLMKKYGVPGMAIAVSVDGKQQIYPYGVASKQTGKPITEQTLFEVGSLSKTFTATLAVYAQQQGKLSFNDPASRYLPELRGSAFDGVSLLNLATHTSGLPLFVPDDVTNDAQLMAYYRAWQPKHPAGSYRVYSNLGIVMLGMIAAKSLDQPFIQAMEQGMLPALGMSHTYVQVPAAQMANYAQGYSKDDKPVRVNPGPLDAKSYGIKSNARDLIRYLDANLQQVKVAHAWRDALAATHVGYYKAGAFTQDLMWENYPYPVKLSRLIEGNNAGMIMNGTPATAITPPQPELRAGWYNKTGSTGGFSTYAVFIPAKNIAVVMLANKWFPNDDRVEAAYHIVQALEKR |
| SRT-2 | ........................................................................E.................................................................................................G...............................................................E.........................QP.................................................................................................................... | 98.68 % |
| SRT-3 | ....................H................................................................................S....H..................................DN...........................G...........R....................I..............N...............E.....................A...QP..E.............V..........................................................................................R.....D.. | 95.50 % |
| SRT-4 | ....................H................................................................................K........................................N...........................G...............................................................E.........................QP.........I...................................................................................................I...... | 97.62 % |
| SST-1 | ....................H........................................................................................................................DN...........................G..............T.............R..................N...............E.............................E..T.....................................................................................................R.....D.. | 96.83 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)
