Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the SRT beta-lactamase family

SRT-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370........
MTKMNRLAAALIAALILPTAQAAQQQDIDAVIQPLMKKYGVPGMAIAVSVDGKQQIYPYGVASKQTGKPITEQTLFEVGSLSKTFTATLAVYAQQQGKLSFNDPASRYLPELRGSAFDGVSLLNLATHTSGLPLFVPDDVTNDAQLMAYYRAWQPKHPAGSYRVYSNLGIVMLGMIAAKSLDQPFIQAMEQGMLPALGMSHTYVQVPAAQMANYAQGYSKDDKPVRVNPGPLDAKSYGIKSNARDLIRYLDANLQQVKVAHAWRDALAATHVGYYKAGAFTQDLMWENYPYPVKLSRLIEGNNAGMIMNGTPATAITPPQPELRAGWYNKTGSTGGFSTYAVFIPAKNIAVVMLANKWFPNDDRVEAAYHIVQALEKR
SRT-2 ........................................................................E.................................................................................................G...............................................................E.........................QP....................................................................................................................  98.68 %
SRT-3 ....................H................................................................................S....H..................................DN...........................G...........R....................I..............N...............E.....................A...QP..E.............V..........................................................................................R.....D..  95.50 %
SRT-4 ....................H................................................................................K........................................N...........................G...............................................................E.........................QP.........I...................................................................................................I......  97.62 %
SRT-C1 ........................................................................E.....................................................................N...........................G...............................................................E.........................QP....................................................................................................................  98.41 %
SRT-C2 ........................................................................E.....................................................................N...........................G...............................................................E.........................QP.............................................----...................................................................  97.35 %
SRT-C3 ......C-............H...........................................................................S....K....H...DV..............................N...........................G...............................................................E.........................SVA.RWPR-RTSVITS...........................................................................E...................I......  92.59 %
SRT-C4 .......................................................Y..L.............................................................TV................................................G...............................................................E.........................QP....................................................T...............................................................  97.62 %
SRT-C5 ........................................................................E.....................................................................N...........................G.....................................V.........................E.........................QP.............................................................................................................I......  97.88 %
C-SRT phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)