Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the SPC beta-lactamase family
SPC-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370........
MTKINRLAAALLAAMILPAGHAADKAEIDAIIQPLMQKYGVPGMAIAVSVDGKQQFYDYGVASKQTGKPITNQTLFEVGSLSKTFTATLAAYAQNEGKLSFAEPASHYLSELRGSAFDRVSLLNLATHTSGLPLFVPDEVTNDAQLMAYYKNWQPPHAVGSYRVYSNLGIGMLGMITAKSLNQPFAQAMEKQLLPALGMNHSYVNVPAAQMDNYAQGYNKKDQPVRVTPGPLDAESYGIKSNAEDLIRYLEANMQVAKVGDKWRKALAATHTGYYRAGVFTQDLMWESYAYPEKLTTLTEGNNAGMIMNGTPATAITPPKQEQGAAWYNKTGSTGGFSTYAVFIPSKKIAVVMLANKWFPNDDRVAATYQLIQALDKR |
| SPC-2 | ............T.............D..............................H...................I...................R...........P........H...................Q...........RQ...T..................................T....G...........TG..E........Q..............A.......Q..............................FQ................VA.PK......................L.Q.T...F..................Q....................S.RIV.....P | 90.74 % |
| SPC-3 | ..........................D..............................H...................I...............................P........H...................Q...........RQ...T.............V....................T....G............G..E........Q..............A.......Q..............................FQ................VA.AK.................T....L.Q.T...F..................Q....................S.RIV.....P | 91.01 % |
| SPC-4 | .............................................................................................................P............................................................................L...........................................................................................................................A..........D.................................................V...... | 98.68 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)
