Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the MIR beta-lactamase family

MIR-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.
MMTKSLSCALLLSVASSAFAAPMSEKQLAEVVERTVTPLMNAQAIPGMAVAVIYQGQPHYFTFGKADVAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEIALGDPVAKYWPELTGKQWQGIRMLDLATYTAGGLPLQVPDEVTDTASLLRFYQNWQPQWKPGTTRLYANASIGLFGALAVKPSGMSYEQAMTTRVFKPLKLDHTWINVPKAEEAHFAWGYREGKAVHVSPGMLDAEAYGVKTNVKDMASWLIANMKPDSLQAPSLKQGIALAQSRYWRVGAMYQGLGWEMLNWPVDAKTVVGGSDNKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQLGIVMLANKSYPNPARVEAAYRILDALQ
MIR-2 ................A........T................................................................................................................................................................................................Y..................................V........................................................................................................................H......  98.69 %
MIR-3 ................A.........................................................................................................................................................................................................Y............................................H.....................................................................................................................  99.21 %
MIR-4 ................A......F..................................................................................................................................................................................................Y............................................H.....................................................................................................................  98.95 %
MIR-5 ..........................................................................................................................................................................................................................Y..................................................................................................................................................................  99.74 %
MIR-6 ..............T.A........T..............................................................S.................................................................................................................................Y..................................................................................................................................................................  98.69 %
MIR-7 ................A.........................................................................................................................................................................................................Y..................................................................................................................................................................  99.48 %
MIR-9 ..........................................................................................................................S...............................................................................................Y..................................V...............................................................................................................................  99.21 %
MIR-10 ..........................................................................................................................................................................................................................Y..................................V...............................................................................................................................  99.48 %
MIR-11 ..............T...........................................................................................................................................................................................................Y..................................................................................................................................................................  99.48 %
MIR-12 ..............T.......................................................................................V...................................................................................................................Y..................................................................................................................................................................  99.21 %
MIR-13 ..............T...........................................................................................................................................................................................................Y.................N................V...............................................................................................................................  98.95 %
MIR-14 ........................................K..............................................................S.....T..............H..E...................N.................................................I....N.N........T....Y.....D......................Q.....VMV........DS..RK..................................E............AR.......L.N....................................................  93.44 %
MIR-15 ................A......................I..................................................................................................................................................................................Y..................................V...............................................................................................................................  98.95 %
MIR-16 ................A.........................................................................................................................................................................................................Y..................................V...............................................................................................................................  99.21 %
MIR-17 ..............T.A.....................................................................................V...................................................................................................................Y..................................V...............................................................................................................................  98.69 %
MIR-18 ..........................................................................................................................................................................................................................Y............................................E.....................................................................................................................  99.48 %
MIR-19 ..........................................................................................................................................................................................................................Y.............................................................C....................................................................................................  99.48 %
MIR-20 ..............T.A........T................................................................................................................................................................................................Y..................................................................................................................................................................  98.95 %
MIR-21 ..............T...........................................................................................................................................................................................................Y..................................V...............................................................................................................................  99.21 %
MIR-22 ..............T.......................................................................................V...................................................................................................................Y..................................V...............................................................................................................................  98.95 %
MIR-23 ..........................................................................................................................................................................................................................Y..............................................S...................................................................................................................  99.48 %
MIR-24 ..............................................................................................................................................................................L...........................................Y..................................................................................................................................................................  99.48 %
MIR-25 ................A.........................................................................................................................................................................................................Y......................................................V...................................................................................I.......................  98.95 %
C-MIR phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)