Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the CMA-CSA-like beta-lactamase family
CMA-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.....
MKSKVSALLMMIVLAGHAQAAPVAPPDAVVKPLMARYQIPGMAVAVSVNGETHFWHYGVASKATRKPVDEKTLFEIGSLSKTFTATLASGAQHEGKLDFSAPASQYLPALKGSAFDHVTLLNLATHTAGTPLFVPDAVKNTAQLMAWYRAWQPEKPVGTERVYSNLGIGLLGMITAKALDKPFSEAMEQGLLKGFGMTHTFINVPDAAMDDYAQGYNKDDKPVRVTPGPLDAESYGLKSGSADLLRYLQIQLGEQEVAPGWRQAINATHNGYYRSGEFTQGMMWEYYPWPSPLSRLVEGNSSQRIMKGLAATAIVPPQPAPEAAWYNKTGSTNGFSTYAVFIPEKRIALIMLANKWFPNDDRVKAAYAIIQQLDK |
| CMA-2 | .........................................................................................A..Q..................................S................................................................RD.................................................................R............................................................................S...................................... | 98.13 % |
| CSA-1 | ......................................................................N..................K..QD......................N........................T...D..............................................RD...........E....N......................................................................L.......................................Q.............................................T...E... | 96.00 % |
| CSA-2 | ......................................................................N..................K..QD...............................................P...D..............................................RD...............G.......................................................................L............................T..........Q.................................................E... | 96.53 % |
Last updated: April 06, 2026.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since March 29th, 2025)
