Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the GOB-11-like beta-lactamase family

GOB-11
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290....
MRNFATLFFLSACLSLS--LNAQVVKEPENMPKEWNQTYEPFRIAGNLYYVGTYDLASYLIVTDKGNILINTGTAESLTIIKGNIQKLGFNYKDIKVLLLTQAHYDHTGALEDFKTETGAKFYADKADADVLKTGGKSDYELGKYGVTFKPITPDRTLKDQDKITLGNTTLTLLHHPGHTKGSCSFIFETKDEKRKYRVLIANMPSIIVDKKFSEVAAYPNIQSDYAYTFGAMKKLDFDLWVASHASQFDLHEKRKEGDPYNPQLFMDKQSYFQNLNDLEKSYLDKIKKDSQDK
GOB-13 ...........V..N.N--...........................................................P.................I..............Q...........T................................................................D...........................T.....................................................N...S..N................  95.89 %
GOB-14 ...........V..D.N--...........................................................P.................I..............Q...........T................................................................D...........................T.....................................................N...S..N................  95.89 %
GOB-15 ...........V..N.N--.........................................................P.P.................I..............Q...........T................................................................D...........................T.....................................................N...S..N................  95.55 %
GOB-19 ...........V....N--...........................................................P.................I............................................M..........................................................................T.............................................................................  97.95 %
GOB-23 .....I.....V...----...........................................................P.................I............................................M..............A.........A.................................................T.............................................................................  96.58 %
GOB-25 ...........V....NLN.....................................T.....................P.................I...................................R...................................................................................T.............................................................................  96.94 %
GOB-26 ...........V....N--..................A........................................P.................I...................................R.......................................................D...........................T.....................................................N...S..N................  96.23 %
GOB-32 ...........V....N--....I.............A........................................P...D.............I...................................R...................................................................................T.............................................................................  96.92 %
GOB-T3 ...........V....N--...........................................................P.................I...................................R...................................................................................T.............................................................................  97.95 %
B3-GOB-11-like phylogenetic tree

Last updated: January 08, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)