Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the PAM beta-lactamase family
PAM-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......
MRFLASLALPLFAANLAVAAPKPLPQLEAYEGLQAWLVPVEPLRISDHVWQIGTASISALLVKTDAGAVLIDGGMPQVADHLLANMKKLGVQPQDLRLILHSHAHIDHVGPLAAIKRATGAVLVSNAESAVLLQRGGADDIHFGSGMLFAPLTPERLVQDGEAVTLGDTTFTVHFTPGHTPGSMSWTWTDTQDGKPLRIAYADSLSAPGYQLRDNARYPHLVDAFRASFAAVRALPCDLLLTPHAEGSGWDYTNAEKPHPAPVSCKAYADKAEQKLDQMLAEQAKSR |
| PAM-2 | ..L..................AQ.......K..D.........................................................A...V.........................M................N..........E.IQTD.................................A..R.........S...........H........E.............................A..AR...Q............AN..K......NK. | 90.24 % |
| PAM-3 | ..L..................AQ.......K..D.........................................................A...V.........................A...........................E.IQTD..............................................S...........H............E.........................A..AR...Q............AN..K......NK. | 91.29 % |
| PAM-5 | .................L................................................................................................................................................T............................................................................................................................ | 99.30 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)
