Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the VIM-2-like beta-lactamase family

VIM-2
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260......
MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRSVVE
VIM-3 ...........................................................K.......................................................................................S......................................................................................................................  99.25 %
VIM-6 ...........................................................R.......................................................................................S......................................................................................................................  99.25 %
VIM-8 ..........................................................................................................................................A...............................................................................................................................  99.62 %
VIM-9 ..........................................................................................................................................I...............................................................................................................................  99.62 %
VIM-10 ..........................................................................................................................................................................................................................................Y...............................  99.62 %
VIM-11 ...................................................................................................................................................S......................................................................................................................  99.62 %
VIM-15 ..................................................................................................................................................................................................F.......................................................................  99.62 %
VIM-16 ......................................................L...................................................................................................................................................................................................................  99.62 %
VIM-17 ...............M..........................................................................................................................................................................................................................................................  99.62 %
VIM-18 ...........................................................R...................................................................................----.......................................................................................................................  98.12 %
VIM-20 ....................................................................................................................................................................................................................................R.....................................  99.62 %
VIM-23 ............................................................................................................................................................................................................S.............................................................  99.62 %
VIM-24 ............................................................................................................................................................................................................L.............................................................  99.62 %
VIM-30 ....................................N.....................................................................................................................................................................................................................................  99.62 %
VIM-31 ........................................................................................................................................................................................................H...........................R.....................................  99.25 %
VIM-36 ...........................................................R..............................................................................................................................................................................................................  99.62 %
VIM-41 ....................................................................................................................................................................................................................N.....................................................  99.62 %
VIM-44 ................................................................................................................................................................................................................................................................N.........  99.62 %
VIM-45 ..................................I.......................................................................................................................................................................................................................................  99.62 %
VIM-46 ...F...............................A......................................................................................................................................................................................................................................  99.25 %
VIM-48 ...F......................................................................................................................................................................................................................................................................  99.62 %
VIM-50 ...................................................................................................................................................S........................................................L.............................................................  99.25 %
VIM-51 ...............................................................................................................................................................................................................V..........................................................  99.62 %
VIM-53 .L.VI.S.................................................................................................................................................................................................................................................................A.  98.12 %
VIM-56 ..T..............................................................................................................................................................................................................G........................................................  99.25 %
VIM-58 ...F.............................................................................................................................................................................................................G........................................................  99.25 %
VIM-60 ............................................................................................................................................................................................................L.......................R.....................................  99.25 %
VIM-62 .......................V..................................................................................................................................................................................................................................................  99.62 %
VIM-63 .................................................................................................................................................................................................................................L........................................  99.62 %
VIM-65 ...................................A...........................................................................................................................................................................V..........................................................  99.25 %
VIM-66 .........................................................................................................................................L..................................................................L.......................R.....................................  98.87 %
VIM-67 ...................................A......................................................................................................................................................................................................................................  99.62 %
VIM-72 .................................................................................................................................................................................................................T........................................................  99.62 %
VIM-73 ......................................................................................................................................................S...................................................................................................................  99.62 %
VIM-74 ...............................................................................................................................................................................................G..........................................................................  99.62 %
VIM-76 ................................................................................................................................................L...........................................................L.......................R.....................................  98.87 %
VIM-77 ...................................................................................................................................................D......................................................................................................................  99.62 %
VIM-80 ......................................................................................................................................................-...................................................................................................................  99.62 %
VIM-81 ................................H.........................................................................................................................................................................................................................................  99.62 %
VIM-82 ...........................................................R.....................................................................................................................................................T........................................................  99.25 %
VIM-84 ...........................................................R................................................................................................................................................L.............................................................  99.25 %
VIM-85 ...........................................................R........................................................N.......................................................................................L.............................................................  98.87 %
VIM-87 .............T............................................................................................................................................................................................................................................................  99.62 %
B1-VIM-2-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)