Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the KLUA beta-lactamase family

KLUA-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.
MMTQSIRRSMLTVMATLPLLFSSATLHAQANSVQQQLEALEKSSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKQSESDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGPDKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRAQLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQPEQKAESRRDVLAAAAKIVTHGF
KLUA-2 .............................T..........................................................................................................................................................................................................G.................V...A....................................  98.63 %
KLUA-5 .............................T..........................G..H..........K...................................................................................................................................................................................V........................................  98.28 %
KLUA-6 ......................R......T..........................................................................................................................................................................................................G.................V...A....................................  98.28 %
KLUA-8 ................................................................................................................................................................................................................................................................QT.................................  99.31 %
KLUA-9 ................................................................................................................................................................................................................................Q............................................D.....................  99.31 %
KLUA-10 .............................T...........................................................N......................................................................................................................................Q.........................V........................................  98.63 %
KLUA-11 ................................................................................................................................................................................................................................Q...............V...P.TH.....................D.....................  97.94 %
KLUA-14 .................................................................................................................................................................................................................................................................................................S.  99.66 %
KLUA-15 .............................T..........................................................................................................................................................................................................G.................V........................................  98.97 %
KLUA-16 .............................T.......K..........................................................................................................................................................................................Q...............................................................R..  98.63 %
KLUA-17 .............................T....................................................L.............................................................................................................................................Q.........................V........................................  98.63 %
A-KLUA phylogenetic tree

Last updated: November 16, 2022.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu