Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
Beta-Lactamase DataBase - Structure and Function Home Enzymes Structures Mutants Kinetics BLAST
Beta-Lactamase DataBase

Sequence alignment for the FONA beta-lactamase family

FONA
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.....
MVRNTLRQTTLMVATVMPLLFGSAPLWAQPANAKANIQQQLSELEKNSGGRLGVALIDTADNSQILYRGDERFPMCSTSKVMAVSALLKQSETDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGPAKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAISLQNLTLGKALAEPQRAQLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQPQQNAEARKDVLAAAAKIVTAGL
FONA-1 .IK....K.....................T................S........................................................................................................................................E...S..L...K...........G.............................I.......................................................E..  95.93 %
FONA-2 ..K....K.............S.......T.........................................................................................................................................................P...S..L...K...........G.............................I.......................................................E..  96.27 %
FONA-3 ..K.I..K.....T...............T................................................................................................................................................................L...K...........G.....................................................................................E..  96.95 %
FONA-4 ..K....K.....................T................S........................................................................................................................................E...S..L...K...........G.............................I.......................................................E..  96.27 %
FONA-5 ....................................................................................................................................................................................................................................................................................................E..  99.66 %
FONA-6 ..K..........................T................S.....................A.........................................................................................................................L...K...........G.....................................................................................E..  97.29 %
FONA-7 ..K..........................S......................................A.........................................................................................................................L...K...........G..........................I..........................................................E..  97.29 %
A-FONA phylogenetic tree

Last updated: November 06, 2021.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu