Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the CME beta-lactamase family

CME-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.........
MKKIILLFILTSQLVLAQH--TSILNDINAVTKDKKATVAVSVLGIENDFQFSNANGNLKMPMLSVFKFHIALAVLNQVDKGNLTLDQKILIKKSDLLENTWSPLREKYPDGNVELPLSEIITYTVAQSDNNGCDILLRLIGGTKTVQKLMDVNGIKNFQIKYNEEEMHKNDVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTIFLMDIMTKTNTGMSKLPGLLPKVRMARKTGSSGKMKNGLTIAENDSGIVTLANGKHYAIAVFVKDSMESEEVNCGMIAQVSKIVWDALNKKK--
CME-2 ...................--......................................................................................................................................V.....................................................................................................................G......I...............NKP  97.98 %
CME-3 ..R.SII.LFF.LF.FS..SKPEL.EK..TI..G......................................................................................................................................................................................................................................................................NKP  91.97 %
CME-4 ...................--......................................................................................................................................V............................................................................................................................I...............NKP  98.32 %
A-CME phylogenetic tree

Last updated: November 16, 2022.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu