Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the BPS beta-lactamase family

BPS-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.....
MNHSPLRRSLLVAAISTPLIGACAPLRGQAKNVAAAERQLRELESTFDGRLGFVALDTATGARIAHRGDERFPFCSTSKMMLCAAVLARSAGEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGPQAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRAQLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTMRNPNAQARDDVIASATRIAARAFA
BPS-1b ................................................................................................................................................M......................................................................................................................................................  99.66 %
BPS-1c ......................................................................................................................................................L................................................................................................................................................  99.66 %
BPS-1d ........................................................................................................................................................T..............................................................................................................................................  99.66 %
BPS-1m ............................................................................................................................................................................S..........................................................................................................................  99.66 %
BPS-2 ........................................................................................................................................................T.....................................................................................................................T........................  99.32 %
BPS-3 ...........I..V.A..V.......DN.R...-..Q.............................A.........F.T..S.........DA.......P...R..V.......K......T................................................T.....I.................R.........T..........................G..............G.........D......V......SR............A.......V  89.15 %
BPS-4 ..............V.A..A........NS....-................................A.........F....S........DDA.......P...R..V.......R......T.....................D..........................T.....I.................R...A.........................L......G..............G.........D......V......SQ..PV......A.A........  88.81 %
BPS-5 ...........A..VFA.........I.NSNG........S....S.G...................A.........F.T..S..I......DAT......P...R..VS...V..K...D..T.......A...............................T........T.....I................LR................DT.....T..A........................G...............IVI.....DK.....N..L...A.....T.G  83.39 %
BPS-6 ........................................................................................................................................................T...................S..........................................................................................................................  99.32 %
BPS-7 .............................................................................F..........................................................................T..............................................................................................................................................  99.32 %
A-BPS phylogenetic tree

Last updated: November 06, 2021.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu