Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the VDA beta-lactamase family
VDA-A-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280..........
MKNILITLTCLFLSSHTVADTLTQQVAQLESQSGGRLGVAVLDTQNNHQWQYRGDERFPMMSTFKALMCASALDLADQNKLSLNDTTTIKESDLVTWSPVTEKLIGQDMTIQQACEATMLMSDNTAANIVLHQIGG-PQQVTQFVRTLDDKVTRLDRYEPELNQATPGDKRDTTSPHAMVTSLNTILLQDGLSEKNQQTLLTWMKNNKISDSLIRSILPQGWSIADRTGAGEQGSRAINALVWNEQHKPIIISLYLTHTELDIAQRNQTLNQVAKLVLEHFSVE------ |
| VDA-A-2 | ..............................T.........................................................................................................-....................F..............................................................................................................................------ | 99.29 % |
| VDA-H-1 | ..KLFLL.GL.AC..A.Y.AN.MKTSPR.KKHIS..I..S.W...TDEH.D..............T.A..TM.SDM.NE..DK.A.AKVE.RNM.V....MDRMAS.TTR.EH....A.............RS...-.RG..T.L.SIG..A.....F..R..E.N........T.N...NT.H.L.EG.A..YESRIQ.KI..QD..V....M..V..K.......S...GF...G.T.MI.K.N...VY..I.I.E.D.SLQA.D.VIA..SQ.I.DEYNTI------ | 53.00 % |
| VDA-H-2 | ..KLFLL.GL.AC..A.Y.AK.NEDISAI.EHIS..I..S.W...TDEH.D..............T.A..TM.SDM.NE..DK.A.AKVE.RNM.V....MDRMA..TTRFEH....A......S..H...RS.W.VHAGG.S.L.SIG..A.....F..R..E.N........T.N...NT.H.L.EG.A..YESRIQ.KI..QD..V....M..V..K.......S...GF...G.T.MI.K.N...VY..I.I.E.D.SLQA.D.VIA..SQ.I.DEVQYYLALAKY | 50.00 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)
