PenA-1

........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......... MTHSSQRRILLLAAATAPLALSLGACAARDATVSDAASPVGAAPASFAALERAAGGRLGVCAIDTATGRRALHRADERFPFCSTFKAMLGAAVLAQSVAHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGPAAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAANLRVL--VLGDALPPAQRAQLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQTRADAKAKDDVIAAATRIASATLA------

PenA-2	....P....................................................................................................................................................................................................S....--....................................................A...................A..................I....RAATRE	96.43 %
PenA-3	...............................A.........................................................................................................................................................................S....--....................................................A...................A..................I....------	98.34 %
PenA-4	........................................................................Y................................................................................................................................S....--....................................................A...................A..................I...G------	98.01 %
PenA-5	....P..........................A......................................................................................................................................................K..................S....--....................................................A...................A..................I....------	97.68 %
PenA-6	....P....................................................................................................................................................................................................S....--...........T......................A.................A...................A..................I....------	97.68 %
PenA-7	....P....................................................................................................................................................................................................S....--...........T........................................A...................A..................I...G------	97.68 %
PenA-2	....P..........................A.........................................................A...............................................................................................................S....--....................................................A...................A..................I....------	97.68 %
PenA-9	...............................A.........................................................A........E......................................................................................................S....--.......A............................................A...................A..................I....------	97.35 %
PenA-10	..........................................V..............................................................................................................................................................S..M.--....................................................A...................A..................IS..G------	97.35 %
PenA-11	...............................A..............L..........................................................................................................................................................S....--...........T........................................A...................A..................I...G------	97.35 %
PenA-12	...............................A.....L..........................A........................................................................................................................................S....--....................................................A...................A..................I...G------	97.35 %
PenA-13	....P..........................A...............................................R.........A...............................................................................................................S....--....................................................A...................A..................I....------	97.35 %
PenA-15	....P.................................R..................................................................................................................................................................S....--.............................................A......A...................A..................I...G------	97.35 %
PenA-16	...............................A........................................Y................A...............................................................................................................S....--.......L............................................A...................A..................I...G------	97.02 %
PenA-17	....................................P.....S..............................................................................................................................................................S....--.......H..........................A.................A...................A..................I...G------	97.02 %
PenA-18	....P......................T...A.........................................................................................................................................................................S....--.......L............................................A...................A..................I...G------	97.02 %
PenA-19	...............................A..........S.............................Y................A...............................................................................................................S....--....................................................A...................A..................I...P------	97.02 %
PenA-20	...............................A.....L..........................A........................A...............................................................................................................S....--....................................................A...................A..................I...G------	97.02 %
PenA-21	....P..............................T.....................................................................................................................................................................S....--.......A......S...................A.................A...................A..................I...G------	96.69 %
PenA-22	....P....................................L-..............................................................................................................................................................S....--.......A..........................A.................A...................A..................I...G------	96.69 %
PenA-23	...............................A..........S.............................................................R................................................................................................S....--............R.....................A.................A...................A..................I....------	97.02 %
PenA-24	.P..P..........................A..........S.............................Y................A...............................................................................................................S....--....................................................A...................A..................I....------	96.69 %
PenA-25	...............................A..........S.....................A.......Y...........I....A...............................................................................................................S....--....................................................A...................A........E.........I....------	96.36 %
PenA-26	....P..........................A...T....................................Y..G.............A...........................................................................................P..............E....S....--....................................................A...................A..................I....------	96.03 %
PenA-27	....P..........................A...T....................................Y..G.............A......................................................S...................................................E....S....--....................................................A...................A..................I....------	96.03 %
PenA-28	...............A......V........A......................................T.............................................S....................................L...............................................S....--.......A............................................A................................T.....I...G------	96.03 %
PenA-29	...............A......V........A...............................................................................Q....S....................................L...............................................S....--.......A.........................A...................................................T.....I...G------	96.03 %
PenA-30	...............A......V........A......A...............................T.............................................S....................................L...............................................S....--.......A.................R...........................................................T.....I...G------	95.70 %
PenA-31	...............................A.....L..........................A........................A..................................Y.....A......................................................................S....--....................................................A...................A...............Q..I...G------	96.03 %
PenA-32	...............A......V........A......................................T.............................................S....................................L...............................................S....--.......A.........................A..................A................................T.....I...G------	95.70 %
PenA-33	...............A......V........A....................................................................................S....................................L...............................................S....--.......A.........................A..................A..M.............................T.....I...G------	95.70 %
PenA-34	...............A......V........A....................................................................................S....................................L...............................................S....VL.......A.........................A..................A..M.............................T.....I...G------	95.07 %
PenA-35	...............A......V........PTDN....G............................................................................S....................................L...............................................S....--.......A.........................A..................A................................T.....I...G------	94.70 %
PenA-37	...............A......V........PTDN....G..............................T.............................................S....................................L...............................................S....--.......A.........................A.....................M.............................T.....I...G------	94.37 %
PenA-38	...............A......VC.......STDN....G............................................................................S....................................L...............................................S....--.......A.........................A..................A......................................I...G------	94.70 %
PenA-39	...............A......V........A......................................T.............................................S....................................L...............................................S....--.......A.........................A.....................M.............................T.....I...G------	95.70 %

Last updated: April 06, 2026.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

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