Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the KLUG beta-lactamase family
KLUG-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.
MMRHRVKRVMLMTTTCISLLLGSAPLYAQANDVQQKLAALEKSSGGRLGVALIDTADNAQTLYRADERFAMCSTSKVMAAAAVLKQSETQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGPDKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRAQLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQPEQKAESRRDVLAAAAKIVTDGN |
| KLUG-2 | ...KS.R.AI....A.V....A.V....H........................N....T................................DL...R..............A..........G.........................G...........D..............................A.......N...D.......M................................................V.......S.P.............R.....Y | 90.38 % |
| KLUG-3 | ...KS.S.AI....A.V....A.V........I....................N....T................................DL...R..............A..........G.........................G.......V...D......................................N...D........................................................V........KP.............R.....Y | 90.72 % |
| KLUG-4 | ...KS.R.AI....A.V....A.V........I....................N....T................................DL...R..............A..........G.........................G.......V...D......................................N...D........................................................V.........P.............R.....Y | 91.07 % |
| KLUG-5 | ...KS.R.AI....A.V....A.V..C..........................N....T................................DL...R..............A..........G.........................G...........D......................................N...D........................................................V........KP.....G.......R.....Y | 90.72 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)
