Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the CumA beta-lactamase family
CumA-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290........
MFKTTFRQTATIAVSLISLLVSPMLWANTNNTIEEQLSTLEKYSQGRLGVALINTEDNSQITYRGEERFAMASTSKVMAVAAVLKESEKQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGPAKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQQLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQQEQDAKYRKDIIVKATEIVTKEISNSPQTK |
CumA-2 | ..........A.........A......DN........N...............................................A..............................T...T..E.................................................................................................N..........V.....................E................N........A..A.............. | 94.97 % |
CumA-3 | ...I................A.............................................................I...............I.T...............A...............................S.............................................................................................................................................F..TS.K. | 96.31 % |
CumA-4 | ..........A.........A......DN........N.................K.............................A..............................T...T..E.................................................................................................N..........V.....................E.........................A..A.............. | 94.97 % |
CumA-5 | ...K......A.........A.AT..........A...E....N......................................................A.................................................SS........................................................................................................E...............K.........A.........FA...... | 94.63 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)