Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the CTX-M-25-like beta-lactamase family

CTX-M-25
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.
MMRKSVRRAMLMTTACVSLLLASVPLCAQANDVQQKLAALEKSSGGRLGVALINTADNTQTLYRADERFAMCSTSKVMAVAAVLKQSETQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGPDKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRAQLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQSEPKAESRRDVLAAAARIVTDGY
CTX-M-26 ...............................................................................A................................................................................................................................................R................D.................................................  98.97 %
CTX-M-39 ...............................................................................A.................................................................................................................................................................D.................................................  99.31 %
CTX-M-41 ...............................................................................A.........................V...................I.....................................................................................................................................................................  98.97 %
CTX-M-89 .................................................................................................................................................................................................................................................D.................................................  99.66 %
CTX-M-91 ...............................................................................................................................................................................................S.................................................D.................................................  99.31 %
CTX-M-94 ...............................................................................A.........................................L.........................................................................................................................................................................  99.31 %
CTX-M-100 ...............................................................................A...................................................................................................................................................................................................................  99.66 %
CTX-M-160 .........................................................................................................V.........................................................................................................................................................................................  99.66 %
CTX-M-217 ...............................................................................A............................S......................................................................................................................................................................................  99.31 %
KLUG-2 .........I................Y.H..................................................A...........D.........S...................L..........................G.......A....................................................................................D.................................................  96.56 %
KLUG-3 ......S..I................Y.....I..............................................A...........D.........S...................L..........................G.......V..................................T...................T.............................D..........................PK.....................  94.85 %
KLUG-4 .........I................Y.....I..............................................A...........D.........S...................L..........................G.......V..................................T...................T.............................D..........................P......................  95.53 %
KLUG-5 .........I.....................................................................A...........D.........S...................L..........................G.......A..................................T...................T.............................D..........................PK......G..............  95.53 %
A-CTX-M-25-like phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)