Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the CRH beta-lactamase family
CRH-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280..........
MFKHLILFASLAAPLTQAVAADPLAVAADKLAKLERDFGGSIGVYAIDTGSGATVANRPNERFPMCSSFKGFLAAGVLAQSQDKPGLLDKRIRYSKAALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGPAALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESAQKLALGKALPEPQRQQLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGVYGTANDFAVIWPPKRAPIVLAVYTKHAKKEAKHSDEVIAAAARAALEAFNVKK |
| CRH-2 | ........................S.......................................L.................E.............T................................................................L.......V........................................................................................................................ | 97.93 % |
| CRH-3 | .......L..IT............S.......................................L...............................T..........................................................R.....L........................................R....................................................................................... | 96.90 % |
| CRH-4 | .......L...T....................................................L...............................T................................................................L.......V........................................................................................................................ | 97.93 % |
Last updated: September 18, 2025.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since March 29th, 2025)
