Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the CME-like beta-lactamase family
CME-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.........
MKKIILLFILTSQLVLAQH--TSILNDINAVTKDKKATVAVSVLGIENDFQFSNANGNLKMPMLSVFKFHIALAVLNQVDKGNLTLDQKILIKKSDLLENTWSPLREKYPDGNVELPLSEIITYTVAQSDNNGCDILLRLIGGTKTVQKLMDVNGIKNFQIKYNEEEMHKNDVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTIFLMDIMTKTNTGMSKLPGLLPKVRMARKTGSSGKMKNGLTIAENDSGIVTLANGKHYAIAVFVKDSMESEEVNCGMIAQVSKIVWDALNKKK-- |
CME-2 | ...................--......................................................................................................................................V.....................................................................................................................G......I...............NKP | 97.98 % |
CME-3 | ..R.SII.LFF.LF.FS..SKPEL.EK..TI..G......................................................................................................................................................................................................................................................................NKP | 91.97 % |
CME-4 | ...................--......................................................................................................................................V............................................................................................................................I...............NKP | 98.32 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)