Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
Beta-Lactamase DataBase - Structure and Function Home Enzymes Structures Mutants Kinetics BLAST
Beta-Lactamase DataBase

Sequence alignment for the CARB beta-lactamase family

CARB-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300........
----------------MKFLLAFSLLIPSVVFASS-SKFQQVEQDVKAIEVSLSARIGVSVLDTQNGEYWDYNGNQRFPLTSTFKTIACAKLLYDAEQGKVNPNSTVEIKKADLVTYSPVIEKQVGQA-ITLDDACFATMTTSDNTAANIILSAVGGPKGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQKKLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQTQASMEERNDAIVKIGHSIFDVYTS-QSR-
CARB-2 MLLYKMCDNQNYGVTY...................-............................................................................................-..........................................................................................................................................................A...................-...-  94.41 %
CARB-3 ----------------...................-............................................................................................-............................................................................L.............................................................................A...................-...-  99.31 %
CARB-4 ----------------..L..V.......M...N.-.........A.V..A....H..I......T.................................EI..K..I.....................-................A......N.L...ES....................E...............N..VN...EL....T..QDG.....Y.................E.........................A.S...........E..IAD.........R...E..S.-...-  86.11 %
CARB-5 ------MNVRKHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LA.H.LET.KR.EHKS.E....S.....L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W.TE...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKTVLMEN..N  43.05 %
CARB-6 ----------------...................-............................................................................................-...........................................................................QL....T...AS.......................VK.S.................I....EKKT..........E...A..........R...E....-...-  94.10 %
CARB-7 ----------------..S..V.A..M........-....S...EI.G..S........AI.......S.....D......................H....L.................L.....KP-...S...L.............VIN...D..SI................V..E...............N..T....QL....T...AS.......................VK.S.................I....EKK...........E...A..........R...E....-...-  84.03 %
CARB-8 ------MDVRKHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LA.H.LET.KR.EHKS.E....S.....L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W.TE...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKTILMEN..N  43.05 %
CARB-9 ----------------..S..V.A..M........-....S...EI.G..S........AI.......S.....D......................H....L.....V...........L.....KP-...S.................VIN...D..SI................V..E...............N..T....QL....T...AS.......................VT.S.................I....EKK...........E...A..........R...E....-...-  84.03 %
CARB-10 ------MDVRQHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LAAH.LET.KR.EHKS.E..........L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W.TE...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKTVLMEN..N  43.05 %
CARB-11 ----------------...................-..................................................................S.........................-..........................................................................................................................................................A...................-...-  99.31 %
CARB-12 ----------------.....V.............-...R........................................................................................-............................S..........................................................K..................................................................A..........R........-...-  97.92 %
CARB-14 ------MDVRKHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LA.H.LET.KR.EHKS.E....S.....L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W.TE...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKIVLMEN..N  43.05 %
CARB-16 ------MDVRKHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LA.H.LET.KR.EHKS.E....S.....L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W.TE...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKTVLMEN..N  43.05 %
CARB-17 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AR.DERNI.VW...MD.LT..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-18 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-19 ----------------..K.FLLAG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-20 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AR.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-21 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...MD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AR.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-22 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TDKR...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..Q...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.22 %
CARB-23 ----------------..K.FLLVG.MVCSTVSYA-.-KLNLNE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-24 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NH.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-25 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.L.H.KE-S---  47.92 %
CARB-26 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LR.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-27 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LT..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-28 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....KD.S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.22 %
CARB-29 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISI..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-30 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...MD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM...S...LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.22 %
CARB-31 ----------------..K.FLLVG.MVYSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-32 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...MD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AR.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...SV...A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LER.KE-S---  47.22 %
CARB-33 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.M.S..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.92 %
CARB-34 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..G...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-35 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NKI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-36 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HSLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-38 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.SLG.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.22 %
CARB-40 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AR.NERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-41 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRVEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-42 ----------------..K.FLLAG.MVCSTLSYA-.-QL--NE.ISLL.QQT.S......W...AD.R...R.DE....M.....L....M.S.MDS..LSK.A.AKVDERSI.VW...MD.LA..N-TRIEH..E.A.LM.......LV.NEI....A..M...T....A........R...ATP..S......N..LN..RTLVE.ET..YESRVQ.KI..QD.K.SDS.M.....T..S.........H.S.G.N.II.K.NHR.VYI...VTE.EL.LQA.DQLVAQ.SQL.LQK.KD-N---  47.57 %
CARB-43 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S...NA.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.22 %
CARB-44 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDNT..YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.22 %
CARB-45 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NA.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..G...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-46 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S...EA.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.22 %
CARB-47 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DESNI.VW...MD.LA..S-TRIEH..E.A.LM.......LV.NEI....A..L...S....A.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-48 ----------------..K.FLLVG.MVCSTVSYA-.-KL--NE.ISL..KQT.G......W...TD.R...R.DE....M.....L...TM.S.MDS..L.K.A.AK.DERNI.VW...MD.LA..N-TRIEH..E.A.LM.......LV.NEI....A..L...S....T.....L..R...A.P..K......N.MVN..HTLMEDN...YESRTQ.KI..QD.K.SDS.M.....K..S........NY.S.G.S.MI.KDNYK.VYI...VTD.DL.LQA.DQL.AQ.SQL.LEH.KE-S---  47.57 %
CARB-49 ------MDVRKHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LA.H.LET.KR.EHKS.E..........L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W.TE...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKTVLMEN..N  43.38 %
CARB-50 ------MDVRQHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LAAH.LET.KR.EHKS.E....S.....L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W.TE...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKTVLMEN..N  42.72 %
CARB-51 ----------------...................-............................................................................................-.....................................................................................................D....................................................A...................-...-  99.31 %
CARB-52 ----------------..L..V.......M...N.-.........A.V..A....H..I......T.................................EI..K..I.....................-................A......N.L...ES...................SE...............N..VN...EL....T..QDG.....Y.................E.........................A.S...........E..IAD.........R...E..S.-...-  85.76 %
CARB-53 ----------------...................-......K.....................................................................................-..........................................................................................................................................................A...................-...-  99.31 %
CARB-54 ------MNVRQHKASF----FSVVITFLCLTLSLNANATDS.LEA.TNA.TE.G....LAAH.LET.KR.EHKS.E....S.....L...NV.QRVDL..ERIDRV.RFSESN.......T..H..KKGMS.AEL.Q..LS....S...F..Q.I....AL.K...S...DT.....W..E...AVP..K......I.MVT..E.L.IDET..IKSRQQ....LKG.E.GDA.F.KGV.SD.IV...T....Y.S.A....M.PPNRK..VAAL.ITE.D..F....AV.A...EQ.AKTVLMEN..N  43.05 %
CARB-55 ----------------....W...H..........-.........................Y..................................................................-..........................................................................................................................................................A...................-...-  98.61 %
CARB-56 ----------------..K.FLLAG.MVCSTLSYA-.-QL--NE.ISLL.QQT.S......W...AD.R...R.DE....M.....L....M.S.MDS..LSK.A.AKVDERSI.VW...MD.LA..N-TRIEH..E.A.LM.......LV.NEI....A..M...T....A........R...ATP..S......N..LN..RTLIE.ET..YESRVQ.KI..QD.K.SDS.M.....T..S.........H.S.G.N.II.K.NHR.VYI...VTE.EL.LQA.DQLVAQ.SQL.LQK.KD-N---  47.57 %
CARB-57 ----------------..K.FLLAG.MVCSTLSYA-.-QL--NE.ISL..QQT.S......W...TD.R...R.DE....M.....L...TM.S.MDS..LSK.A.AKVDERSI.VW...MD.LA..N-TRVEH..E.A.LM.......LV.NEI....A..M...T....A.....L..R...ATP..N......N.MVN..RTLIE.ET..YESRVQ.KI..QD.K.SDS.M.....T..S.........H.S.G.N.II.K.NHR.VYI...VTE.EL.LQA.DQL.AQ.SQL.LQK.KD-N---  47.22 %
CARB-58 ----------------..L................-............................................................................................-..........................................................................................................................................................A...................-...-  99.31 %
A-CARB phylogenetic tree

Last updated: November 20, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)