Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the BI-like beta-lactamase family
BcI-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310..
MEGMMILKNKRMLKIGICVGILGLSITSLEAFTGESLQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTISYRPNERFAFASTYKALAAGVLLQQNSIDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGPKGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRKILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSKDEKEAIYDNQLIAEATKVIVKALR |
BcI-2 | .K..IV....K.....M............VT...GA...............................................A..........................TKK.D.........................T..........Y..........H.............Q....V...D...............................A.....NH..N...K...............V..N...A...............I....................G.T.........AE...N.F. | 88.78 % |
BcI-P3 | ------M...K.....M............VT...GA...............................................A..........................TKK.D.........................T..........Y..........H.............K....V...D........................R...D........HQ..N...................V.....DA...............I......S...............T......K..AE.VID.IK | 86.22 % |
BcI-P4 | ---...............................GA......Q..........................V................S.........................T......F........................................................K....V...D.....................R.......................................V......................I......................S..........E......K | 93.91 % |
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since December 3rd, 2023)