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Ambler class |
Protein name |
PDB code |
Resolution (Å) |
Release date |
UniProt code |
PubMed ID |
DOI |
PDB |
Mutations |
Ligands |
Space group |
Unit cell parameters |
Z value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ▲ ▼ | ▲ ▼ | ▲ ▼ | ▲ ▼ | ▲ ▼ | ▲ ▼ | ||||||||
| A | TEM-1 | 1AXB | 2.00 | 1998-10-28 | P62593 | 9485412 | 10.1021/BI972501B | pdb | *FOS | P 21 21 21 | 42.040 60.970 88.910 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1BT5 | 1.80 | 1999-09-02 | P62593 | pdb | V84I A184V | *IM2 SO4 | P 21 21 21 | 41.420 62.010 89.330 ♦ 90.00 90.00 90.00 | 4 | ||
| A | TEM-1 | 1BTL | 1.80 | 1995-01-26 | P62593 | 8356032 | 10.1002/PROT.340160406 | pdb | SO4 | P 21 21 21 | 43.100 64.400 91.200 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1CK3 | 2.28 | 1999-08-18 | P62593 | 10423234 | 10.1021/BI990758Z | pdb | N276D V84I A184V | P 21 21 21 | 41.820 60.360 88.650 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1ERM | 1.70 | 2000-05-10 | P62593 | 10820001 | 10.1021/BI992505B | pdb | *BJI BHD | P 21 21 21 | 63.030 89.060 42.160 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1ERO | 2.10 | 2000-05-10 | P62593 | 10820001 | 10.1021/BI992505B | pdb | *BJP | P 21 21 21 | 61.190 89.280 42.100 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1ERQ | 1.90 | 2000-05-10 | P62593 | 10820001 | 10.1021/BI992505B | pdb | *BJH | P 21 21 21 | 63.222 89.039 42.088 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1ESU | 2.00 | 2000-05-03 | P62593 | 15299797 | 10.1107/S0907444994014496 | pdb | S235A | SO4 | P 21 21 21 | 41.931 63.245 88.746 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1FQG | 1.70 | 2000-11-01 | P62593 | 1436034 | 10.1038/359700A0 | pdb | E166N | *PNM | P 21 21 21 | 62.200 88.300 41.600 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1JTD | 2.30 | 2001-10-03 | P62593 | 11573088 | 10.1038/NSB1001-848 | pdb | CA | P 21 21 21 | 47.525 84.918 147.694 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1JTG | 1.73 | 2001-10-17 | P62593 | 11573088 | 10.1038/NSB1001-848 | pdb | V84I A184V | CA | P 21 21 21 | 45.800 126.300 158.300 ♦ 90.00 90.00 90.00 | 8 |
| A | TEM-1 | 1JVJ | 1.73 | 2002-03-06 | P62593 | 11870868 | 10.1002/PROT.10058.ABS | pdb | N132A | *IM2 K | P 21 21 21 | 41.303 61.685 89.139 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1JWP | 1.75 | 2002-06-05 | P62593 | 12079336 | 10.1016/S0022-2836(02)00400-X | pdb | M182T | PO4 | P 21 21 21 | 41.465 61.691 89.205 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1JWV | 1.85 | 2002-06-05 | P62593 | 12079336 | 10.1016/S0022-2836(02)00400-X | pdb | G238A | *CB4 K | P 21 21 21 | 41.365 61.665 89.401 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1JWZ | 1.80 | 2002-06-05 | P62593 | 12079336 | 10.1016/S0022-2836(02)00400-X | pdb | E104K R164S M182T | *105 | P 21 21 21 | 72.002 34.546 105.489 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1LHY | 2.00 | 2002-09-11 | P62593 | 12058046 | 10.1074/JBC.M204212200 | pdb | R243S | PO4 | P 21 21 21 | 41.532 59.670 88.097 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1LI0 | 1.61 | 2002-09-11 | P62593 | 12058046 | 10.1074/JBC.M204212200 | pdb | M69I M182T | BCT K | P 21 21 21 | 41.222 60.504 88.712 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1LI9 | 1.52 | 2002-09-11 | P62593 | 12058046 | 10.1074/JBC.M204212200 | pdb | M69V | K PO4 | P 21 21 21 | 41.371 59.604 88.291 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1M40 | 0.85 | 2002-07-17 | P62593 | 11996574 | 10.1021/JA0259640 | pdb | M182T | *CB4 K PO4 | P 21 21 21 | 41.313 61.641 89.252 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1NXY | 1.60 | 2003-08-26 | P62593 | 12859188 | 10.1021/BI034242Y | pdb | M182T | *SM2 K | P 21 21 21 | 73.625 34.560 105.360 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1NY0 | 1.75 | 2003-08-26 | P62593 | 12859188 | 10.1021/BI034242Y | pdb | M182T | *NBF K PO4 | P 21 21 21 | 41.289 58.967 88.630 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1NYM | 1.20 | 2003-08-26 | P62593 | 12859188 | 10.1021/BI034242Y | pdb | M182T | *CXB K PO4 | P 21 21 21 | 41.344 61.659 89.129 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1NYY | 1.90 | 2003-08-26 | P62593 | 12859188 | 10.1021/BI034242Y | pdb | M182T | *105 | P 21 21 21 | 41.498 61.953 89.065 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1PZO | 1.90 | 2004-03-09 | P62593 | 15037085 | 10.1016/J.JMB.2003.12.068 | pdb | M182T | $CBT | P 21 21 21 | 41.887 61.038 88.683 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1PZP | 1.45 | 2004-03-09 | P62593 | 15037085 | 10.1016/J.JMB.2003.12.068 | pdb | N100R | $FTA | P 21 21 21 | 41.553 60.673 89.092 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 1S0W | 2.30 | 2004-02-10 | P00810 | 15618400 | 10.1073/PNAS.0407280102 | pdb | CA | P 21 21 21 | 45.785 125.507 158.763 ♦ 90.00 90.00 90.00 | 8 | |
| A | TEM-1 | 1TEM | 1.95 | 1997-05-15 | P62593 | pdb | *ALP | P 21 21 21 | 42.100 63.100 88.800 ♦ 90.00 90.00 90.00 | 4 | |||
| A | TEM-1 | 1XPB | 1.90 | 1997-04-01 | P62593 | 15299797 | 10.1107/S0907444994014496 | pdb | SO4 | P 21 21 21 | 41.786 62.721 88.841 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1XXM | 1.90 | 2005-01-18 | P62593 | 15618400 | 10.1073/PNAS.0407280102 | pdb | E104A Y105A V84I | CA | P 21 21 21 | 45.706 124.473 156.951 ♦ 90.00 90.00 90.00 | 8 |
| A | TEM-1 | 1YT4 | 1.40 | 2005-07-12 | P62593 | 15981999 | 10.1021/BI0502700 | pdb | S130G | P 21 21 21 | 41.601 59.707 88.360 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 1ZG4 | 1.55 | 2005-05-17 | P62593 | 16041072 | 10.1107/S0907444905014356 | pdb | P 21 21 21 | 42.020 62.840 89.460 ♦ 90.00 90.00 90.00 | 4 | ||
| A | TEM-1 | 1ZG6 | 2.10 | 2005-05-17 | P62593 | 16041072 | 10.1107/S0907444905014356 | pdb | S70G | P 21 21 21 | 41.990 62.650 89.490 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 2B5R | 1.65 | 2006-04-11 | P62593 | 17070843 | 10.1016/J.JMB.2006.09.076 | pdb | Y105N V84I E104Y | P 21 21 21 | 45.799 124.473 157.256 ♦ 90.00 90.00 90.00 | 8 | |
| A | TEM-1 | 2V1Z | 1.60 | 2008-06-24 | P62593 | 21425229 | 10.1002/CBIC.201000568 | pdb | E219R Q247R V64I A248K T249K E84K M250T A164V | ZN | P 21 21 21 | 47.113 70.609 78.313 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 2V20 | 1.67 | 2008-06-24 | P62593 | 21425229 | 10.1002/CBIC.201000568 | pdb | E219R Q247R V64I A248K T249K E84K M250T A164V | SO4 ZN | P 21 21 21 | 46.080 72.142 73.495 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 3C7U | 2.20 | 2008-10-07 | Q79DR3 | 18840610 | 10.1074/JBC.M804089200 | pdb | P 1 21 1 | 49.090 129.476 80.130 ♦ 90.00 91.86 90.00 | 4 | ||
| A | TEM-1 | 3C7V | 2.07 | 2008-10-07 | Q79DR3 | 18840610 | 10.1074/JBC.M804089200 | pdb | P 1 21 1 | 48.671 129.044 78.898 ♦ 90.00 91.20 90.00 | 4 | ||
| A | TEM-1 | 3CMZ | 1.92 | 2008-11-25 | P62593 | 18822298 | 10.1016/J.JMB.2008.09.009 | pdb | L201P | PO4 | P 21 21 21 | 41.218 59.140 87.802 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 3DTM | 2.00 | 2008-08-05 | Q79DR3 | 18706424 | 10.1016/J.JMB.2008.07.082 | pdb | E147G V80I R273L I208M L201P P62S M182T A224V I246V | P 21 21 21 | 39.820 79.680 87.070 ♦ 90.00 90.00 90.00 | 4 | |
| A | TEM-1 | 3GMW | 2.10 | 2009-03-31 | A5PHA6 | 19332077 | 10.1016/J.JMB.2009.03.058 | pdb | PO4 | P 1 | 45.418 48.757 106.137 ♦ 103.24 91.29 90.18 | 2 | |
| A | TEM-1 | 3JYI | 2.70 | 2009-10-06 | P62593 | 19812041 | 10.1074/JBC.M109.053819 | pdb | N170G | EPE PO4 | P 43 21 2 | 88.099 88.099 500.352 ♦ 90.00 90.00 90.00 | 48 |
| A | TEM-1 | 3TOI | 1.90 | 2012-05-16 | Q79DR3 | 22545913 | 10.1021/BI2018738 | pdb | R120G R241H I208M T265M T195S M182T A224V I56V | P 21 21 21 | 42.003 47.525 258.827 ♦ 90.00 90.00 90.00 | 8 | |
| A | TEM-1 | 4GKU | 1.92 | 2012-10-10 | P62593 | pdb | P 21 21 21 | 47.009 72.817 74.723 ♦ 90.00 90.00 90.00 | 4 | ||||
| A | TEM-1 | 4IBR | 2.20 | 2013-04-03 | P62593 | 23542341 | 10.1016/J.JMB.2013.03.033 | pdb | L200A N51A R119G A41G E103K T262M G237S M181T | CA MES | C 1 2 1 | 136.240 46.600 39.000 ♦ 90.00 93.87 90.00 | 4 |
| A | TEM-1 | 4IBX | 2.68 | 2013-04-03 | P62593 | 23542341 | 10.1016/J.JMB.2013.03.033 | pdb | L201A N52A R120G A42G T265M M182T | CA MES SO4 | P 2 21 21 | 39.900 239.000 159.910 ♦ 90.00 90.00 90.00 | 20 |
| A | TEM-1 | 4MEZ | 2.05 | 2014-10-15 | P62593 | pdb | M68L M69T | CL GOL SO4 | P 1 | 34.333 55.071 77.681 ♦ 70.83 81.22 71.84 | 2 | ||
| A | TEM-1 | 4RVA | 1.44 | 2015-03-04 | P62593 | 25713062 | 10.1074/JBC.M114.633438 | pdb | E166Y L201P P167G W165Y | BCT | P 21 21 21 | 59.045 59.505 86.260 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 4RX2 | 2.31 | 2015-03-04 | P62593 | 25713062 | 10.1074/JBC.M114.633438 | pdb | E166Y M182T P167G W165Y | SO4 | P 1 | 60.320 83.300 95.920 ♦ 90.06 89.97 90.02 | 8 |
| A | TEM-1 | 4RX3 | 1.39 | 2015-03-04 | P62593 | 25713062 | 10.1074/JBC.M114.633438 | pdb | E166Y P167G S70G W165Y | FLC | P 21 21 21 | 58.920 60.140 88.770 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 4OP5 | 1.05 | 2015-05-20 | Q9AGJ5 | pdb | A183V A41G R119G N51A L200A K103E T262M | CA MES PG4 | C 1 2 1 | 153.600 46.100 34.500 ♦ 90.00 93.30 90.00 | 4 | ||
| A | TEM-1 | 4OP8 | 1.95 | 2015-05-20 | Q8KMX3 | pdb | A183V A41G R119G N51A L200A K103E | CA PG4 SO4 | C 1 2 1 | 154.360 47.040 34.920 ♦ 90.00 92.63 90.00 | 4 | ||
| A | TEM-1 | 4OPQ | 1.70 | 2015-05-20 | Q8KMX3 | pdb | A183V A41G R119G R163S N51A L200A K103E | CA PEG PG4 SO4 | C 1 2 1 | 154.900 47.200 34.890 ♦ 90.00 92.82 90.00 | 4 | ||
| A | TEM-1 | 4OPR | 1.45 | 2015-05-20 | Q8KMX3 | pdb | A183V A41G R119G N51A L200A K103E | CA PG4 SO4 | C 1 2 1 | 153.830 46.180 34.410 ♦ 90.00 93.12 90.00 | 4 | ||
| A | TEM-1 | 4OPY | 1.75 | 2015-05-20 | Q9AGJ5 | pdb | A183V A41G R119G N51A L200A K103E T262M | CA PG4 SO4 | C 1 2 1 | 154.960 47.070 34.970 ♦ 90.00 93.17 90.00 | 4 | ||
| A | TEM-1 | 4OPZ | 1.45 | 2015-05-20 | Q8KMX3 | pdb | A183V A41G R119G N51A L200A K103E | *2UL ACT CA EDO | C 1 2 1 | 155.560 47.040 34.680 ♦ 90.00 92.46 90.00 | 4 | ||
| A | TEM-1 | 4OQ0 | 1.42 | 2015-05-20 | Q8KMX3 | pdb | A183V A41G R119G R163S N51A L200A K103E | *2UL CA EDO PEG | C 1 2 1 | 152.760 46.180 34.470 ♦ 90.00 92.72 90.00 | 4 | ||
| A | TEM-1 | 4OQG | 2.40 | 2015-05-20 | Q79DR3 | pdb | *2UL ZN | P 43 21 2 | 81.690 81.690 497.920 ♦ 90.00 90.00 90.00 | 48 | |||
| A | TEM-1 | 4OQH | 1.70 | 2015-05-20 | Q9AGJ5 | pdb | A183V A41G R119G N51A L200A K103E T262M | *2UL CA EDO | C 1 2 1 | 155.540 47.030 34.620 ♦ 90.00 92.50 90.00 | 4 | ||
| A | TEM-1 | 4OQI | 1.13 | 2015-05-20 | Q8KMX3 | pdb | A183V A41G R119G R163S N51A L200A K103E | CA SO4 | C 1 2 1 | 152.930 46.400 34.430 ♦ 90.00 93.22 90.00 | 4 | ||
| A | TEM-1 | 4ZJ1 | 1.54 | 2015-05-20 | P62593 | 26038548 | 10.1073/PNAS.1507741112 | pdb | V2164OU | 4OU GOL MES PEG | P 21 21 21 | 45.470 47.240 128.330 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 4ZJ2 | 1.80 | 2015-05-20 | P62593 | 26038548 | 10.1073/PNAS.1507741112 | pdb | E166N | *4OV | P 21 21 21 | 46.461 47.044 127.580 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 4ZJ3 | 1.70 | 2015-05-20 | P62593 | 26038548 | 10.1073/PNAS.1507741112 | pdb | E166N S704OV V2164OU | *4OV 4OU | P 21 21 21 | 46.290 47.025 128.309 ♦ 90.00 90.00 90.00 | 4 |
| A | TEM-1 | 5HVI | 1.64 | 2017-06-28 | P62593 | pdb | M182T | P 1 21 1 | 60.663 84.156 95.703 ♦ 90.00 90.07 90.00 | 8 | |||
| A | TEM-1 | 5HW1 | 1.70 | 2017-06-28 | P62593 | pdb | M182T | XE | P 1 21 1 | 60.690 84.610 95.940 ♦ 90.00 90.06 90.00 | 8 | ||
| A | TEM-1 | 5HW5 | 1.41 | 2017-06-28 | P62593 | pdb | M182T | XE | P 1 21 1 | 60.440 84.620 96.011 ♦ 90.00 90.58 90.00 | 8 | ||
| A | TEM-1 | 5I52 | 1.75 | 2017-06-28 | P62593 | pdb | I263N M182T | P 1 21 1 | 59.987 83.509 95.784 ♦ 90.00 90.06 90.00 | 8 | |||
| A | TEM-1 | 5I63 | 1.95 | 2017-06-28 | P62593 | pdb | I263N M182T | XE | P 1 21 1 | 60.070 84.200 96.220 ♦ 90.00 89.97 90.00 | 8 | ||
| A | TEM-1 | 5IQ8 | 2.06 | 2017-06-28 | P62593 | pdb | A224C G283C M182T | P 1 21 1 | 60.858 84.705 96.344 ♦ 90.00 90.00 90.00 | 8 | |||
| A | TEM-1 | 5KKF | 1.82 | 2017-06-28 | P62593 | pdb | I263L M182T | P 1 21 1 | 60.500 84.030 94.920 ♦ 90.00 90.42 90.00 | 8 | |||
| A | TEM-1 | 5KPU | 1.50 | 2017-08-09 | P62593 | pdb | I263L M182T | XE | P 1 21 1 | 60.430 84.050 95.610 ♦ 90.00 90.00 90.00 | 8 | ||
| A | TEM-1 | 6APA | 1.86 | 2018-08-22 | P62593 | pdb | I263A M182T | P 1 21 1 | 60.669 84.292 95.914 ♦ 90.00 90.00 90.00 | 8 | |||
| A | TEM-1 | 6AYK | 1.44 | 2018-09-12 | P62593 | pdb | I263A M182T | XE | P 1 21 1 | 60.645 84.751 95.971 ♦ 90.00 90.23 90.00 | 8 | ||
| A | TEM-1 | 6B2N | 2.00 | 2018-01-17 | P62593 | 29296672 | 10.1021/ACSCENTSCI.7B00465 | pdb | M182N | SO4 | P 1 21 1 | 81.910 49.660 122.160 ♦ 90.00 90.10 90.00 | 8 |
| A | TEM-1 | 7U6Q | 1.90 | 2022-09-07 | C4NV37 | pdb | M182T | SO4 | P 21 21 21 | 60.730 96.330 154.200 ♦ 90.00 90.00 90.00 | 12 | ||
| A | TEM-1 | 8DDZ | 1.45 | 2022-09-07 | P62593 | pdb | A237Y M182T | P 1 21 1 | 60.610 83.770 95.660 ♦ 90.00 90.23 90.00 | 8 | |||
| A | TEM-1 | 8DE0 | 1.72 | 2022-09-07 | P62593 | pdb | M182T | *NXL | P 1 21 1 | 60.650 83.690 95.570 ♦ 90.00 90.19 90.00 | 8 | ||
| A | TEM-1 | 8DE1 | 1.56 | 2022-09-07 | P62593 | pdb | A237Y M182T | *NXL | P 1 21 1 | 60.610 83.570 95.860 ♦ 90.00 90.44 90.00 | 8 | ||
| A | TEM-1 | 8DE2 | 2.45 | 2022-09-07 | P62593 | pdb | A237Y M182T | *NXL | P 1 21 1 | 60.930 86.070 96.940 ♦ 90.00 90.00 90.00 | 8 | ||
| A | TEM-1 | 8OF9 | 3.11 | 2023-05-31 | 37214973 | 10.1101/2023.05.09.539914 | pdb | ZN | P 43 | 114.972 114.972 49.181 ♦ 90.00 90.00 90.00 | 8 |
Statistics (number of structures): Overall (1663); class A (626); subclass B1 (403); subclass B2 (16); subclass B3 (104); class C (246); class D (268).
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu