Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Structures

Ambler
class
Protein
name
PDB
code
Resolution
(Å)
Release
date
UniProt
code
PubMed
ID
DOI
PDB
Mutations
Ligands
Space
group
Unit cell parameters
Z
value
ASFC-14EQI1.382012-05-23Q6JP75 2303030010.1021/JA304460Jpdb EDO NA P 1 21 142.330 85.430 70.280 ♦ 90.00 103.27 90.004
ASFC-14EUZ1.082012-05-23Q6JP75 2303030010.1021/JA304460JpdbS70A $MEM EDO HAR NA P 21 21 2159.060 61.910 79.010 ♦ 90.00 90.00 90.004
ASFC-14EV41.302012-05-23Q6JP75 2303030010.1021/JA304460JpdbE166A *MER EDO HAR P 21 21 2159.185 61.955 79.127 ♦ 90.00 90.00 90.004
ASFC-16DMH1.302018-12-19Q6JP75 3045785810.1021/ACS.JMEDCHEM.8B01292pdbE166A G255A K270R *MER EDO HAR P 21 21 2159.185 61.955 79.127 ♦ 90.00 90.00 90.004
Legend for ligands: * Ligand covalently-bound to active site residues; $ Non-covalent ligand (Michaelis complex); # Ligand coordinated to active site metal ions.

Statistics (number of structures): Overall (1538); class A (578); subclass B1 (364); subclass B2 (15); subclass B3 (97); class C (222); class D (262).

Last updated: January 22, 2023.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu