Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Structures

Ambler
class
Protein
name
PDB
code
Resolution
(Å)
Release
date
UniProt
code
PubMed
ID
DOI
PDB
Mutations
Ligands
Space
group
Unit cell parameters
Z
value
APenP-11I2S1.702002-03-13P00808 1182753310.1021/BI015789Kpdb CIT NA P 1 21 147.362 106.817 63.901 ♦ 90.00 94.43 90.004
APenP-11I2W1.702002-03-13P00808 1182753310.1021/BI015789Kpdb *CFX OUT P 1 21 147.344 106.372 63.873 ♦ 90.00 94.18 90.004
APenP-11MBL2.001994-01-31P00808 843396510.1093/PROTEIN/6.1.11pdbE166A SO4 P 1 21 167.200 94.100 43.800 ♦ 90.00 104.50 90.004
APenP-12BLM2.001990-10-15P00808 232625210.1002/PROT.340070205pdb P 1 21 166.800 90.700 43.600 ♦ 90.00 104.50 90.004
APenP-13LY31.802011-03-02P00808 pdbE166C P 21 21 2143.438 74.936 79.034 ♦ 90.00 90.00 90.004
APenP-13LY41.802011-03-02P00808 pdbE166C *PNM P 21 21 2143.454 74.700 78.989 ♦ 90.00 90.00 90.004
APenP-13M2J1.802011-03-16P00808 pdbE166C $F5M SO4 P 1 21 143.354 92.340 66.415 ♦ 90.00 104.84 90.004
APenP-13M2K3.502011-03-16P00808 pdbE166C *PCZ P 1 21 143.538 91.524 66.302 ♦ 90.00 104.22 90.004
APenP-13SH72.502011-07-27P00808 2170532510.1074/JBC.M110.198895pdbE166C $BB0 P 1 21 143.490 91.000 66.160 ♦ 90.00 104.36 90.004
APenP-13SH82.002011-07-27P00808 2170532510.1074/JBC.M110.198895pdbE166C *CED P 1 21 143.330 91.730 66.110 ♦ 90.00 104.00 90.004
APenP-13SH91.902011-07-27P00808 2170532510.1074/JBC.M110.198895pdbE166C *PCZ BB0 P 1 21 143.386 91.626 66.008 ♦ 90.00 104.50 90.004
APenP-13SOI1.732011-12-14P00808 2249605310.1002/PRO.2076pdbW210F W229F W251F CIT P 1 21 142.760 110.090 54.130 ♦ 90.00 89.97 90.004
APenP-14BLM2.001993-01-15P00808 185686710.1016/0022-2836(91)90023-Ypdb SO4 P 1 21 166.800 90.700 43.600 ♦ 90.00 104.50 90.004
APenP-14M3K1.482014-08-06P00808 pdb CL P 1 21 151.818 42.940 74.818 ♦ 90.00 105.29 90.002
APenP-14N1H3.002014-10-08P00808 pdb P 1 21 159.088 89.821 75.749 ♦ 90.00 95.17 90.004
APenP-14N921.932014-09-10P00808 2502003110.1021/BI401609HpdbE166S P 143.310 46.190 66.280 ♦ 78.43 75.71 69.362
APenP-14N9K1.932014-09-10P00808 2502003110.1021/BI401609HpdbE166S *CED P 143.370 45.800 66.120 ♦ 77.85 75.41 69.002
APenP-14N9L2.302014-09-10P00808 2502003110.1021/BI401609HpdbE166S *DWZ P 1 21 143.260 90.960 66.200 ♦ 90.00 104.24 90.004
APenP-15GHX1.242017-01-25P00808 pdbE166H ACY EDO P 143.331 45.849 66.139 ♦ 77.84 75.65 69.092
APenP-15GHY2.102017-01-25P00808 pdbE166H *CED P 143.240 45.940 65.990 ♦ 76.84 75.58 69.072
APenP-15GHZ1.932017-01-25P00808 pdbE166H *CED P 143.290 45.490 66.100 ♦ 77.81 75.48 68.762
APenP-15LWF2.562017-11-15P00808 pdb ACT P 21 21 2147.278 121.691 137.029 ♦ 90.00 90.00 90.008
APenP-15ZFL1.502019-03-20P00808 pdbE166Y EDO EPE P 143.230 48.395 66.213 ♦ 76.29 75.38 69.562
APenP-15ZFT1.932019-03-20P00808 pdbE166Y *CED P 143.240 45.880 66.090 ♦ 77.63 75.51 69.272
APenP-15ZG62.002019-03-20P00808 pdbE166Y *CED P 143.292 46.459 65.981 ♦ 77.43 75.53 69.342
Legend for ligands: * Ligand covalently-bound to active site residues; $ Non-covalent ligand (Michaelis complex); # Ligand coordinated to active site metal ions.

Statistics (number of structures): Overall (1429); class A (543); subclass B1 (348); subclass B2 (15); subclass B3 (82); class C (221); class D (220).

Last updated: November 06, 2021.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu