Beta-Lactamase DataBase (BLDB): Structure and Function

Ambler class	Protein name	PDB code	Resolution (Å)	Release date	UniProt code	PubMed ID	DOI	PDB	Mutations	Ligands	Space group	Unit cell parameters	Z value
▲ ▼	▲ ▼	▲ ▼	▲ ▼	▲ ▼							▲ ▼
D	OXA-24	2JC7	2.50	2007-03-20	Q8RLA6	17374723	10.1073/PNAS.0607557104	pdb		SO4	P 41 21 2	102.200 102.200 86.100 ♦ 90.00 90.00 90.00	8
D	OXA-24	3FV7	2.00	2010-02-02	Q8RLA6	20822105	10.1021/JA104092Z	pdb		*MXS KCX	P 41 21 2	102.390 102.390 84.220 ♦ 90.00 90.00 90.00	8
D	OXA-24	3FYZ	2.10	2010-02-09	Q8RLA6	20822105	10.1021/JA104092Z	pdb		*MXC KCX PG4	P 41 21 2	102.760 102.760 83.160 ♦ 90.00 90.00 90.00	8
D	OXA-24	3FZC	2.00	2010-02-09	Q8RLA6	20822105	10.1021/JA104092Z	pdb		*MXF KCX PG4	P 41 21 2	102.520 102.520 84.480 ♦ 90.00 90.00 90.00	8
D	OXA-24	3G4P	1.97	2010-02-23	Q8RLA6	20822105	10.1021/JA104092Z	pdb		KCX	P 41 21 2	102.310 102.310 84.010 ♦ 90.00 90.00 90.00	8
D	OXA-24	3MBZ	2.60	2011-03-16	Q8RLA6	20822105	10.1021/JA104092Z	pdb		*MXC KCX SO4	P 41 21 2	103.083 103.083 85.802 ♦ 90.00 90.00 90.00	8
D	OXA-24	3PAE	2.10	2011-01-19	Q8RLA6	21215758	10.1016/J.JMB.2010.12.042	pdb	K84D	*DRW SO4	P 41	102.334 102.334 85.450 ♦ 90.00 90.00 90.00	8
D	OXA-24	3PAG	2.25	2011-01-19	Q8RLA6	21215758	10.1016/J.JMB.2010.12.042	pdb	V130D	*DRW SO4	P 41	102.274 102.274 85.449 ♦ 90.00 90.00 90.00	8
D	OXA-24	3ZNT	1.95	2014-01-08	Q8RLA6			pdb		*TBE KCX SO4	P 41 21 2	102.898 102.898 86.344 ♦ 90.00 90.00 90.00	8
D	OXA-24	4F94	2.40	2013-08-14	Q8RLA6			pdb	K84D	*1S6 SO4	P 41 21 2	102.334 102.334 87.444 ♦ 90.00 90.00 90.00	8
D	OXA-24	4WM9	2.40	2014-12-03	Q8RLA6	25406838	10.1021/CB500703P	pdb		*NXL CO2 EDO SO4	P 41 21 2	102.180 102.180 87.920 ♦ 90.00 90.00 90.00	8
D	OXA-24	5TG4	1.44	2017-01-11	Q8RLA6	27997706	10.1002/PRO.3100	pdb		*JW1 3GR ABA BCT KCX MEE SO4	P 41 21 2	102.347 102.347 85.438 ♦ 90.00 90.00 90.00	8
D	OXA-24	5TG5	1.75	2017-01-11	Q8RLA6	27997706	10.1002/PRO.3100	pdb		*JW8 ABA BCT KCX MEE SO4	P 41 21 2	102.974 102.974 86.730 ♦ 90.00 90.00 90.00	8
D	OXA-24	5TG6	1.78	2017-01-11	Q8RLA6	27997706	10.1002/PRO.3100	pdb		*J4W ABA BCT KCX SO4	P 41 21 2	102.418 102.418 85.049 ♦ 90.00 90.00 90.00	8
D	OXA-24	5TG7	2.28	2017-01-11	Q8RLA6	27997706	10.1002/PRO.3100	pdb		*JW3 ABA BCT KCX MEE SO4	P 41 21 2	103.083 103.083 86.437 ♦ 90.00 90.00 90.00	8
D	OXA-24	5VFD	1.93	2017-06-07	Q8RLA6			pdb		^#9CM *9CP KCX SO4	P 41 21 2	102.680 102.680 84.770 ♦ 90.00 90.00 90.00	8
D	OXA-24	6B22	1.93	2018-08-01	Q8RLA6	29627985	10.1021/ACS.JMEDCHEM.8B00091	pdb		*C8Y CL	P 41 21 2	102.539 102.539 84.312 ♦ 90.00 90.00 90.00	8
D	OXA-24	6MPQ	1.95	2019-02-27	Q8RLA6	30862744	10.1128/MBIO.00159-19	pdb		*JXG CL KCX	P 41 21 2	102.562 102.562 87.005 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RP8	2.28	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb	K84D	*ID1 SO4	P 41 21 2	102.164 102.164 85.657 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RP9	1.94	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb	V130D	HIW ID1 BCT SO4	P 41 21 2	102.304 102.304 86.921 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RPA	2.27	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb	K84D	*MER BCT PEG SO4	P 41 21 2	102.770 102.770 86.020 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RPB	1.97	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb	V130D	*MER BCT	P 41 21 2	102.391 102.391 85.647 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RPC	2.58	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb	K84D	^$6H7 BCT SO4	P 41 21 2	102.828 102.828 87.433 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RPD	1.95	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb	V130D	*1RG BCT SO4	P 41 21 2	102.696 102.696 85.803 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RPE	1.53	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb		*1RG BCT KCX SO4	P 41 21 2	102.808 102.808 84.380 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RPF	1.90	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb		4J6 DRW BCT KCX SO4	P 41 21 2	102.699 102.699 84.468 ♦ 90.00 90.00 90.00	8
D	OXA-24	7RPG	1.62	2022-07-06	Q8RLA6	35709986	10.1016/J.JBC.2022.102127	pdb	K84D	*CEF PEG SO4	P 41 21 2	102.447 102.447 86.352 ♦ 90.00 90.00 90.00	8
D	OXA-24	8CUL	2.01	2023-04-05	Q8RLA6		10.3390/ANTIBIOTICS12040644	pdb		*0N3 KCX	P 41 21 2	102.585 102.585 86.174 ♦ 90.00 90.00 90.00	8
D	OXA-24	8CUM	1.49	2023-04-05	Q8RLA6		10.3390/ANTIBIOTICS12040644	pdb		*OZ0 KCX SO4	P 41 21 2	102.190 102.190 85.760 ♦ 90.00 90.00 90.00	8
D	OXA-24	8CUO	1.47	2023-04-05	Q8RLA6		10.3390/ANTIBIOTICS12040644	pdb		*OZ9 KCX SO4	P 41 21 2	102.180 102.180 86.430 ♦ 90.00 90.00 90.00	8

Legend for ligands: * Ligand covalently-bound to active site residues; ^$ Non-covalent ligand (Michaelis complex); ^# Ligand coordinated to active site metal ions.

Statistics (number of structures): Overall (1663); class A (626); subclass B1 (403); subclass B2 (16); subclass B3 (104); class C (246); class D (268).

Structures