Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Structures

Ambler
class
Protein
name
PDB
code
Resolution
(Å)
Release
date
UniProt
code
PubMed
ID
DOI
PDB
Mutations
Ligands
Space
group
Unit cell parameters
Z
value
AKPC-22OV51.852007-05-01Q93LQ9 1744173410.1021/BI700300Updb BCN P 31116.245 116.245 52.001 ♦ 90.00 90.00 120.009
AKPC-23C5A1.232008-08-05A8DS27 1862577210.1128/AAC.00163-08pdbC-ter 292VNGQQ296 deleted CIT P 21 21 2147.890 65.990 72.130 ♦ 90.00 90.00 90.004
AKPC-23DW01.602008-07-29A8DS27 1862577210.1128/AAC.00163-08pdb P 1 21 156.300 91.300 73.100 ♦ 90.00 112.60 90.004
AKPC-23E2K2.102009-08-04Q93LQ9 1973193210.1021/BI9007963pdbG175S P 21 21 2141.240 76.198 241.350 ♦ 90.00 90.00 90.008
AKPC-23E2L1.872009-08-04Q93LQ9 1973193210.1021/BI9007963pdbG175S SEE C 1 2 1162.243 66.391 82.205 ♦ 90.00 101.28 90.008
AKPC-23RXW1.262012-03-21Q9F663 2233090910.1128/AAC.06099-11pdb *SR3 CIT P 21 21 2149.051 66.288 71.776 ♦ 90.00 90.00 90.004
AKPC-23RXX1.622012-03-21Q9F663 2233090910.1128/AAC.06099-11pdb *NPB P 21 21 2150.348 66.558 73.598 ♦ 90.00 90.00 90.004
AKPC-24ZBE1.802016-01-27Q9F663 2634056310.1371/JOURNAL.PONE.0136813pdb *NXL CIT P 21 21 2151.315 66.695 73.208 ♦ 90.00 90.00 90.004
AKPC-25EEC1.872016-02-03Q9F663 2672949110.1128/AAC.02643-15pdb *ZXM SO4 P 1 21 151.853 77.883 64.773 ♦ 90.00 108.67 90.004
AKPC-25LL71.402018-02-21A0A0H4IUK8 pdb *6YV EDO P 21 21 2149.033 65.764 72.210 ♦ 90.00 90.00 90.004
AKPC-25MGI1.502018-03-14Q848S6 pdb *6YV P 21 21 2149.409 66.218 72.344 ♦ 90.00 90.00 90.004
AKPC-25UJ31.452017-04-26Q9F663 2838806510.1021/ACS.JMEDCHEM.7B00158pdb $CE4 GOL P 2 21 2156.930 58.780 76.840 ♦ 90.00 90.00 90.004
AKPC-25UJ41.402017-04-26Q9F663 2838806510.1021/ACS.JMEDCHEM.7B00158pdb $SFR GOL P 2 21 2157.140 59.130 77.380 ♦ 90.00 90.00 90.004
AKPC-25UL81.152017-04-26Q9F663 2838806510.1021/ACS.JMEDCHEM.7B00158pdb GOL SO4 P 2 21 2155.800 60.200 78.620 ♦ 90.00 90.00 90.004
AKPC-26B1F1.442018-08-01Q9F663 2962798510.1021/ACS.JMEDCHEM.8B00091pdb *C8Y CIT EDO P 134.540 37.432 82.339 ♦ 92.33 90.05 95.252
AKPC-26B1H1.802018-08-01Q9F663 2962798510.1021/ACS.JMEDCHEM.8B00091pdb *C8Y ACT CL SO4 P 134.487 37.372 81.831 ♦ 87.78 89.96 84.532
AKPC-26B1J1.602018-08-01Q9F663 2962798510.1021/ACS.JMEDCHEM.8B00091pdb *C8V CIT EDO P 134.440 37.416 82.128 ♦ 92.31 90.04 95.262
AKPC-26B1W1.732018-08-01Q9F663 2962798510.1021/ACS.JMEDCHEM.8B00091pdb *C8V CL SO4 P 134.528 37.348 82.068 ♦ 87.66 89.71 84.312
AKPC-26B1X1.452018-08-01Q9F663 2962798510.1021/ACS.JMEDCHEM.8B00091pdb *C9D CIT EDO P 134.493 37.436 82.235 ♦ 92.30 90.21 95.082
AKPC-26B1Y1.802018-08-01Q9F663 2962798510.1021/ACS.JMEDCHEM.8B00091pdb *CD7 CL SO4 P 134.529 37.349 82.070 ♦ 87.66 89.71 84.312
AKPC-26D151.302019-04-17Q9F663 pdb $TWB GOL P 2 21 2156.850 59.090 78.180 ♦ 90.00 90.00 90.004
AKPC-26D161.402019-04-17Q9F663 pdb $FUJ GOL P 2 21 2156.560 59.520 77.730 ♦ 90.00 90.00 90.004
AKPC-26D171.452019-04-17Q9F663 pdb $VKE GOL P 2 21 2156.480 59.400 77.920 ♦ 90.00 90.00 90.004
AKPC-26D181.352019-04-17Q9F663 pdb $GTV GOL P 2 21 2156.610 59.680 77.690 ♦ 90.00 90.00 90.004
AKPC-26D191.452019-04-17Q9F663 pdb $YKG GOL P 2 21 2156.500 59.740 77.620 ♦ 90.00 90.00 90.004
AKPC-26J8Q1.792019-07-17Q93LQ9 3126939810.1021/ACS.JMEDCHEM.9B00735pdb *BHU ACY PEG SO4 P 3 2 1165.159 165.159 94.895 ♦ 90.00 90.00 120.0024
AKPC-26JN32.222019-07-17Q93LQ9 3126939810.1021/ACS.JMEDCHEM.9B00735pdb *BX6 ACY PEG P 3 2 1165.515 165.515 94.681 ♦ 90.00 90.00 120.0024
AKPC-26JN41.902019-07-17Q93LQ9 3126939810.1021/ACS.JMEDCHEM.9B00735pdb *BX9 ACT ACY PEG P 3 2 1164.785 164.785 94.683 ♦ 90.00 90.00 120.0024
AKPC-26JN51.972019-07-17Q93LQ9 3126939810.1021/ACS.JMEDCHEM.9B00735pdb *BXU P 3 2 1164.757 164.757 94.499 ♦ 90.00 90.00 120.0024
AKPC-26M7I1.702019-04-17Q9F663 3094207810.1021/ACSINFECDIS.9B00052pdb $J84 GOL P 2 21 2156.743 59.244 76.277 ♦ 90.00 90.00 90.004
AKPC-26MEY1.422019-04-17Q9F663 3094207810.1021/ACSINFECDIS.9B00052pdb $O5E ACT P 2 21 2156.050 59.860 77.041 ♦ 90.00 90.00 90.004
AKPC-26MLL1.862019-04-17Q9F663 3094207810.1021/ACSINFECDIS.9B00052pdb $N1G GOL P 2 21 2157.112 58.445 74.563 ♦ 90.00 90.00 90.004
AKPC-26MNP2.202019-04-17Q9F663 3094207810.1021/ACSINFECDIS.9B00052pdb $1CE GOL P 2 21 2156.347 59.768 77.094 ♦ 90.00 90.00 90.004
AKPC-26QW91.042019-08-21Q9F663 3138366410.1128/AAC.00564-19pdb *MK7 GOL JJT SO4 P 21 21 259.925 78.535 55.843 ♦ 90.00 90.00 90.004
AKPC-26TD00.992020-01-22Q9F663 pdb *4D6 GOL SO4 P 21 21 259.917 77.938 55.726 ♦ 90.00 90.00 90.004
AKPC-26TD11.202020-01-22Q9F663 pdb *KJK GOL SO4 P 21 21 260.557 79.761 56.021 ♦ 90.00 90.00 90.004
AKPC-26V1J1.302020-03-25Q9F663 3215040710.1021/ACS.JMEDCHEM.9B01976pdb *RM9 GOL QNA SO4 P 2 21 2155.660 59.990 78.160 ♦ 90.00 90.00 90.004
AKPC-26V7I1.252020-08-12Q9F663 3277854610.1128/AAC.00398-20pdb *4D6 GOL SO4 P 2 21 2155.770 59.970 77.720 ♦ 90.00 90.00 90.004
AKPC-26XD51.202020-12-09Q9F663 pdbN170A GOL SO4 P 2 21 2156.259 60.050 77.990 ♦ 90.00 90.00 90.004
AKPC-26XD71.652020-12-09Q9F663 pdbN170A $ZZ7 GOL P 2 21 2156.830 59.380 77.310 ♦ 90.00 90.00 90.004
AKPC-26XJ82.052020-12-09Q9F663 pdbN170A $8YF P 2 21 2156.599 59.360 77.620 ♦ 90.00 90.00 90.004
AKPC-26Z211.302020-12-23Q9F663 3325732010.1074/JBC.RA120.016461pdbE166Q CL GOL SO4 P 21 21 260.200 78.440 55.960 ♦ 90.00 90.00 90.004
AKPC-26Z231.312020-12-23Q9F663 3325732010.1074/JBC.RA120.016461pdbE166Q *CEF GOL SO4 P 21 21 260.137 78.912 55.655 ♦ 90.00 90.00 90.004
AKPC-26Z241.252020-12-23Q9F663 3325732010.1074/JBC.RA120.016461pdbE166Q *CAZ SO4 P 21 21 260.270 77.207 55.408 ♦ 90.00 90.00 90.004
AKPC-27A611.252021-02-24Q9F663 3361815910.1016/J.EJMECH.2021.113257pdbE166Q *R0B GOL SO4 P 21 21 260.535 80.033 56.003 ♦ 90.00 90.00 90.004
AKPC-27E9A2.252021-08-04Q93LQ9 3425924910.1039/D1CC03026Dpdb *J00 ACY GOL PEG P 3 2 1165.421 165.421 94.860 ♦ 90.00 90.00 120.0024
AKPC-27LJK1.812021-05-26Q93LQ9 3402222510.1016/J.JBC.2021.100799pdbF72Y P 134.325 37.310 82.178 ♦ 92.43 90.41 94.622
AKPC-27LK81.432021-05-26Q93LQ9 3402222510.1016/J.JBC.2021.100799pdbT215P NA P 21 21 2167.840 71.660 92.200 ♦ 90.00 90.00 90.008
AKPC-27LLB1.672021-05-26Q9F663 3402222510.1016/J.JBC.2021.100799pdbS70G T215P $8YL P 134.495 37.292 82.128 ♦ 91.39 90.37 93.792
AKPC-27LLH2.102021-05-26Q9F663 3402222510.1016/J.JBC.2021.100799pdbF72Y *IM2 P 134.609 37.123 83.655 ♦ 88.12 88.38 85.482
AKPC-27LNL1.822021-05-26Q9F663 3402222510.1016/J.JBC.2021.100799pdbS70G T215P $8YF P 134.673 37.743 82.706 ♦ 91.54 90.37 93.842
AKPC-27LR91.472022-08-10Q9F663 pdbS70G T215P $8YF P 134.673 37.743 82.706 ♦ 91.54 90.37 93.842
AKPC-27TB70.992022-03-02Q9F663 pdbD179N CIT P 21 21 2151.040 66.251 72.441 ♦ 90.00 90.00 90.004
AKPC-27TBX3.162022-03-02Q9F663 pdbD179Y C 1 2 1123.262 88.248 77.046 ♦ 90.00 109.76 90.008
AKPC-27TC11.162022-03-02Q9F663 pdbD179N *4D6 PO4 P 21 21 2151.209 66.021 72.950 ♦ 90.00 90.00 90.004
AKPC-27TI21.752022-10-12Q9F663 3535886410.1016/J.BMC.2022.116722pdb *ZXQ EDO P 4180.100 80.100 44.760 ♦ 90.00 90.00 90.004
AKPC-27VQN2.342022-10-26Q9F663 pdb *7TC SO4 P 1 21 164.193 127.539 76.303 ♦ 90.00 104.29 90.008
Legend for ligands: * Ligand covalently-bound to active site residues; $ Non-covalent ligand (Michaelis complex); # Ligand coordinated to active site metal ions.

Statistics (number of structures): Overall (1530); class A (576); subclass B1 (362); subclass B2 (15); subclass B3 (96); class C (222); class D (259).

Last updated: November 16, 2022.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu