Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Structures

Ambler
class
Protein
name
PDB
code
Resolution
(Å)
Release
date
UniProt
code
PubMed
ID
DOI
PDB
Mutations
Ligands
Space
group
Unit cell parameters
Z
value
ACTX-M-441BZA1.801999-04-27Q47066 992578610.1006/JMBI.1998.2432pdbE166A SO4 P 32 2 173.309 73.309 99.374 ♦ 90.00 90.00 120.006
ACTX-M-441IYO1.802002-12-11Q47066 1222110210.1074/JBC.M207884200pdbE166A *CEF SO4 P 32 2 172.581 72.581 98.179 ♦ 90.00 90.00 120.006
ACTX-M-441IYP2.002002-12-11Q47066 1222110210.1074/JBC.M207884200pdbE166A *CEP SO4 P 32 2 173.229 73.229 100.229 ♦ 90.00 90.00 120.006
ACTX-M-441IYQ2.102002-12-11Q47066 1222110210.1074/JBC.M207884200pdbE166A *PNM SO4 P 32 2 172.799 72.799 99.467 ♦ 90.00 90.00 120.006
ACTX-M-441IYS1.652003-10-14Q47066 1296248710.1021/BI0342822pdb SO4 P 32 2 172.592 72.592 97.891 ♦ 90.00 90.00 120.006
ACTX-M-441WE41.702005-03-15Q47066 1559582910.1021/BI048488UpdbG238C A26M SO4 P 32 2 172.705 72.705 98.268 ♦ 90.00 90.00 120.006
ACTX-M-442WYX2.102010-01-12Q47066 2003625910.1016/J.JMB.2009.12.036pdbE166A R274N R276N P 32 2 172.993 72.993 98.365 ♦ 90.00 90.00 120.006
ACTX-M-442XQZ2.102010-12-22Q47066 2116841110.1016/J.FEBSLET.2010.12.017pdbR274N R276N P 32 2 172.956 72.956 98.526 ♦ 90.00 90.00 120.006
ACTX-M-442XR02.202010-12-22Q47066 2116841110.1016/J.FEBSLET.2010.12.017pdbR274N R276N SO4 P 32 2 173.500 73.500 99.330 ♦ 90.00 90.00 120.006
ACTX-M-442ZQ70.942009-07-28Q47066 pdbE166A R274N R276N SO4 P 32 2 172.545 72.545 97.656 ♦ 90.00 90.00 120.006
ACTX-M-442ZQ81.032009-07-28Q47066 1934278510.1107/S1744309109008240pdbR274N R276N SO4 P 32 2 172.511 72.511 97.477 ♦ 90.00 90.00 120.006
ACTX-M-442ZQ91.072009-07-28Q47066 pdbE166A R274N R276N $CLS *CEO SO4 SPA P 32 2 172.421 72.421 97.518 ♦ 90.00 90.00 120.006
ACTX-M-442ZQA0.952009-07-28Q47066 pdbE166A R274N R276N *PCZ SO4 P 32 2 172.522 72.522 97.960 ♦ 90.00 90.00 120.006
ACTX-M-442ZQC1.072009-07-28Q47066 pdbE166A R274N R276N *AZR SO4 P 32 2 172.293 72.293 97.578 ♦ 90.00 90.00 120.006
ACTX-M-442ZQD1.192009-07-28Q47066 pdbE166A R274N R276N *CAZ SO4 P 32 2 172.413 72.413 97.665 ♦ 90.00 90.00 120.006
ACTX-M-444BD01.212013-01-09Q47066 2325559410.1074/JBC.M112.436238pdbR274N R276N *BZB SO4 P 32 2 172.500 72.500 97.670 ♦ 90.00 90.00 120.006
ACTX-M-444BD12.002013-01-16Q47066 2325559410.1074/JBC.M112.436238pdbR274N R276N *BZB P 32 2 173.429 73.429 99.112 ♦ 90.00 90.00 120.006
ACTX-M-444C3Q2.202014-07-09Q47066 10.1107/S1600576714010772pdbR274N R276N *BZB P 32 2 172.889 72.889 98.189 ♦ 90.00 90.00 120.006
ACTX-M-444X691.422015-07-01Q47066 2608943910.1093/JAC/DKV166pdbA26G *OP0 EDO P 1 21 151.533 72.982 63.052 ♦ 90.00 109.29 90.004
ACTX-M-445KSC2.102016-11-09Q47066 2779537810.1128/AAC.01636-16pdbR271N R273N E165A *AZR P 32 2 173.296 73.296 99.093 ♦ 90.00 90.00 120.006
ACTX-M-445KMW1.102017-03-01Q47066 pdbR271N R273N E165A $PNN *PNM SO4 P 32 2 172.262 72.262 98.193 ♦ 90.00 90.00 120.006
ACTX-M-446C781.752018-03-21Q47066 10.1021/ACSCATAL.7B04114pdbS70A R274N R276N P 32 2 173.400 73.400 99.390 ♦ 90.00 90.00 120.006
ACTX-M-446C791.102018-03-21Q47066 10.1021/ACSCATAL.7B04114pdbS70A R274N R276N $CE3 SO4 P 32 2 172.720 72.720 98.944 ♦ 90.00 90.00 120.006
ACTX-M-446C7A1.052018-03-21Q47066 10.1021/ACSCATAL.7B04114pdbS70A R274N R276N SO4 P 32 2 171.825 71.825 96.534 ♦ 90.00 90.00 120.006
ACTX-M-446U581.902020-02-19A3FFV8 3203804210.1107/S2059798319016334pdbR276N E166Q SO4 P 32 2 173.543 73.543 99.721 ♦ 90.00 90.00 120.006
Legend for ligands: * Ligand covalently-bound to active site residues; $ Non-covalent ligand (Michaelis complex); # Ligand coordinated to active site metal ions.

Statistics (number of structures): Overall (1530); class A (576); subclass B1 (362); subclass B2 (15); subclass B3 (96); class C (222); class D (259).

Last updated: November 16, 2022.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu