Beta-Lactamase DataBase (BLDB): Structure and Function

Ambler class	Protein name	PDB code	Resolution (Å)	Release date	UniProt code	PubMed ID	DOI	PDB	Mutations	Ligands	Space group	Unit cell parameters	Z value
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A	CTX-M-14	1YLT	1.10	2005-04-19	Q9L5C7	15811373	10.1016/J.JMB.2005.02.010	pdb		SO4 SUC	P 21 21 21	41.467 62.420 86.742 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	1YLZ	1.35	2005-04-26	Q9L5C7	15826180	10.1021/JA042850A	pdb		*CB4 PO4	P 1 21 1	45.310 106.892 47.880 ♦ 90.00 101.87 90.00	4
A	CTX-M-14	4PM5	1.26	2014-12-31	G8XD06	25489790	10.1021/bi501195g	pdb	S70G	^$CE3 SO4	P 21 21 21	41.550 62.680 86.130 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	4PM6	1.56	2014-12-31	G8XD06	25489790	10.1021/bi501195g	pdb	S70G	SO4	P 21 21 21	41.550 62.280 86.200 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	4PM7	1.29	2014-12-31	G8XD06	25489790	10.1021/bi501195g	pdb	S237A S70G	^$CE3	P 21 21 21	41.500 62.630 86.140 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	4PM8	1.17	2014-12-31	G8XD06	25489790	10.1021/bi501195g	pdb	S237A S70G	SO4	P 21 21 21	41.500 62.190 86.080 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	4PM9	1.45	2014-12-31	G8XD06	25489790	10.1021/bi501195g	pdb	R276A S237A S70G	^$CE3	P 21 21 21	41.530 61.737 86.675 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	4PMA	1.40	2014-12-31	G8XD06	25489790	10.1021/bi501195g	pdb	R276A S237A S70G	SO4	P 21 21 21	41.742 62.380 86.701 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	4UA6	0.79	2015-06-24	H6UQI0	26057252	10.1021/JACS.5B00749	pdb		K PCA PO4	P 1 21 1	45.106 106.581 47.716 ♦ 90.00 102.23 90.00	4
A	CTX-M-14	4UA7	0.89	2015-06-24	H6UQI0	26057252	10.1021/JACS.5B00749	pdb		^$3GK PCA PO4	P 1 21 1	45.079 106.947 47.761 ♦ 90.00 101.77 90.00	4
A	CTX-M-14	4UA9	0.84	2015-06-24	H6UQI0	26057252	10.1021/JACS.5B00749	pdb		*CB4 PCA PO4	P 1 21 1	45.074 106.632 47.684 ♦ 90.00 102.18 90.00	4
A	CTX-M-14	4UAA	0.86	2015-06-24	H6UQI0	26057252	10.1021/JACS.5B00749	pdb		^$3GK PCA PO4	P 1 21 1	44.968 106.692 47.664 ♦ 90.00 102.08 90.00	4
A	CTX-M-14	4XXR	1.18	2015-03-18	Q9L5C7	25753149	10.1039/C5CC00904A	pdb	E166A	^$JSC ^$JSD ^$JSE K	P 1 21 1	44.899 106.775 47.903 ♦ 90.00 101.87 90.00	4
A	CTX-M-14	5TOP	1.18	2017-11-08	H6UQI0	29095570	10.1111/FEBS.14315	pdb	S45G S70G	^$7G4 ^$JSC ^$JSE K PCA RU	P 1 21 1	45.093 106.821 47.933 ♦ 90.00 101.66 90.00	4
A	CTX-M-14	5TOY	1.30	2017-11-08	H6UQI0	29095570	10.1111/FEBS.14315	pdb	E166A	^$JSC ^$JSD K PO4 RU SUC	P 1 21 1	45.012 106.787 47.759 ♦ 90.00 101.76 90.00	4
A	CTX-M-14	5TW6	1.70	2017-06-28	Q9L5C7	28613873	10.1021/ACS.BIOCHEM.7B00176	pdb	E166A P167S	*CAZ EDO	P 32 2 1	41.540 41.540 231.151 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	5TWD	1.70	2017-06-28	Q9L5C7	28613873	10.1021/ACS.BIOCHEM.7B00176	pdb	P167S		P 32 2 1	41.600 41.600 231.932 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	5TWE	1.50	2017-06-28	Q9L5C7	28613873	10.1021/ACS.BIOCHEM.7B00176	pdb	P167S S70G	^$CAZ	P 32 2 1	41.610 41.610 232.234 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	5U53	1.40	2017-06-28	H6UQI0	28613873	10.1021/ACS.BIOCHEM.7B00176	pdb		*CAZ NO3	P 41 21 2	42.030 42.030 262.860 ♦ 90.00 90.00 90.00	8
A	CTX-M-14	5UJO	1.35	2017-02-08	A0A1B3B7F6	—	10.1021/ACS.ORGANOMET.6B00888	pdb		^$LSI *8CY K	P 1 21 1	44.961 107.351 47.956 ♦ 90.00 101.36 90.00	4
A	CTX-M-14	5VLE	0.85	2017-11-08	H6UQI0	29095570	10.1111/FEBS.14315	pdb	E166A	^$JSC ^$JSD ^$JSE K PCA PO4 RU	P 1 21 1	44.745 106.418 47.611 ♦ 90.00 102.38 90.00	4
A	CTX-M-14	5VTH	2.20	2017-06-28	Q9L5C7	28613873	10.1021/ACS.BIOCHEM.7B00176	pdb	E166A P167S		P 32 2 1	41.690 41.690 233.052 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	6BT6	1.05	2018-06-13	A0A1B3B7F6	29844038	10.1128/AAC.02563-17	pdb	S237A	^$3GK PCA	P 1 21 1	45.190 107.130 47.850 ♦ 90.00 101.52 90.00	4
A	CTX-M-14	6CYK	1.70	2018-10-10	Q9L5C7			pdb	N106S	ACT	P 1 21 1	45.210 107.160 47.800 ♦ 90.00 101.72 90.00	4
A	CTX-M-14	6CYN	1.60	2018-10-10	Q9L5C7			pdb	N106S D240G		P 32	83.238 83.238 231.982 ♦ 90.00 90.00 120.00	24
A	CTX-M-14	6CYQ	1.70	2018-10-10	Q9L5C7			pdb	N106S S70G	^$CE4 GOL	P 32	83.375 83.375 232.058 ♦ 90.00 90.00 120.00	24
A	CTX-M-14	6CYU	1.82	2018-10-10	Q9L5C7			pdb	N106S D240G S70G	^$CE4	P 32 2 1	41.399 41.399 230.610 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	6D7H	1.80	2019-07-24	H6UQI0			pdb		K PO4	P 32 2 1	41.710 41.710 232.524 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	6D7I	2.00	2019-07-24	H6UQI0			pdb	D233N		P 32 2 1	41.809 41.809 231.951 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	6GTH	1.69	2018-10-10	D2D9A0		10.1038/S41467-018-06156-7	pdb		*NXL	P 32 2 1	41.840 41.840 233.280 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	6MD8	1.40	2019-04-17		30942078	10.1021/ACSINFECDIS.9B00052	pdb		^$J84 DMS PCA	P 1 21 1	45.202 106.878 47.781 ♦ 90.00 101.89 90.00	4
A	CTX-M-14	6MIA	1.40	2019-04-17	H6UQI0	30942078	10.1021/ACSINFECDIS.9B00052	pdb		^$1CE	P 1 21 1	45.340 107.185 47.881 ♦ 90.00 101.33 90.00	4
A	CTX-M-14	6MZ1	1.00	2019-11-20	A0A2S1PK93	32123084	10.1073/pnas.1922203117	pdb		*NXL K NA PCA PO4	P 1 21 1	45.220 106.720 47.810 ♦ 90.00 101.79 90.00	4
A	CTX-M-14	6MZ2	0.83	2019-11-20	A0A2S1PK93	32123084	10.1073/pnas.1922203117	pdb		*NXL K NA PCA PO4	P 1 21 1	45.161 106.842 47.913 ♦ 90.00 101.82 90.00	4
A	CTX-M-14	6OOF	1.24	2020-07-01	A0A2S1PK93			pdb		^$R6Z PCA	P 1 21 1	45.161 107.211 47.884 ♦ 90.00 101.66 90.00	4
A	CTX-M-14	6OOJ	1.40	2020-07-01	A0A2S1PK93			pdb		^$J1X PCA	P 1 21 1	45.096 106.929 47.830 ♦ 90.00 101.61 90.00	4
A	CTX-M-14	6OOK	1.40	2020-07-01	A0A2S1PK93			pdb		^$MZV PCA PO4	P 1 21 1	45.003 106.725 47.736 ♦ 90.00 101.73 90.00	4
A	CTX-M-14	6UNB	1.30	2019-10-30	A0A2S1PK93			pdb		*TJ7 PCA PO4	P 1 21 1	45.110 106.460 47.670 ♦ 90.00 101.92 90.00	4
A	CTX-M-14	6V5E	2.30	2020-04-22	Q9L5C7	32299911	10.1074/JBC.RA119.012489	pdb	D240G P167S	SEE	P 41 21 2	42.237 42.237 261.638 ♦ 90.00 90.00 90.00	8
A	CTX-M-14	6V6G	1.50	2020-04-22	Q9L5C7	32299911	10.1074/JBC.RA119.012489	pdb	D240G E166A P167S	NA PEG	P 32 2 1	41.428 41.428 231.066 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	6V6P	1.55	2020-04-22	Q9L5C7	32299911	10.1074/JBC.RA119.012489	pdb	D240G E166A	PEG SO4	P 41 21 2	41.930 41.930 259.190 ♦ 90.00 90.00 90.00	8
A	CTX-M-14	6V7H	1.00	2020-08-12	A0A2S1PK93	32778546	10.1128/AAC.00398-20	pdb		*4D6 K PCA PO4 WXM	P 1 21 1	45.300 106.695 47.865 ♦ 90.00 101.64 90.00	4
A	CTX-M-14	6V7T	1.34	2020-04-22	Q9L5C7	32299911	10.1074/JBC.RA119.012489	pdb	D240G E166A	*CAZ	P 1 21 1	45.110 107.330 47.750 ♦ 90.00 99.86 90.00	4
A	CTX-M-14	6V83	1.80	2020-04-22	Q9L5C7	32299911	10.1074/JBC.RA119.012489	pdb	D240G E166A P167S	*CAZ	P 41 21 2	42.357 42.357 262.692 ♦ 90.00 90.00 90.00	8
A	CTX-M-14	6V8V	1.80	2020-04-22	Q9L5C7	32299911	10.1074/JBC.RA119.012489	pdb	D240G E166A P167S	*CAZ	P 32 2 1	41.273 41.273 231.629 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	6VHS	1.28	2020-08-26	A0A2S1PK93	32658473	10.1021/ACS.JMEDCHEM.0C00579	pdb		*X57 PCA PO4	P 1 21 1	45.250 106.920 47.870 ♦ 90.00 101.81 90.00	4
A	CTX-M-14	6VNU	1.47	2020-04-01	A0A1B3B7F6	32182393	10.1002/CBIC.202000054	pdb		*TDJ 7G4 K	P 1 21 1	45.152 106.894 47.908 ♦ 90.00 101.68 90.00	4
A	CTX-M-14	7K2W	1.40	2020-11-04	A0A2H4FY00			pdb		*CEF	P 32 2 1	41.654 41.654 232.309 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	7K2X	1.80	2020-11-04	A0A2H4FY00			pdb		GOL	P 32	83.373 83.373 232.091 ♦ 90.00 90.00 120.00	24
A	CTX-M-14	7K2Y	1.62	2020-11-04	A0A2H4FY00			pdb		*AIX	P 32 2 1	41.630 41.630 231.473 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	7Q0Y	1.30	2022-04-13	A0A2S1JJX2	35365689	10.1038/S41598-022-09392-6	pdb		*BO2 ACT CL GOL	P 21 21 21	41.303 62.331 86.244 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	7Q0Z	1.00	2022-04-13	D2D9A0	35365689	10.1038/S41598-022-09392-6	pdb	Q25E	GOL SO4	P 21 21 21	41.361 62.497 86.421 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	7Q11	1.14	2022-04-13	D2D9A0	35365689	10.1038/S41598-022-09392-6	pdb		*6V8 CL DMS SO4	P 21 21 21	41.485 62.372 87.187 ♦ 90.00 90.00 90.00	4
A	CTX-M-14	7U70	1.36	2023-03-22	H6UQI0			pdb		^$LW0	P 1 21 1	45.250 106.800 47.730 ♦ 90.00 101.84 90.00	4
A	CTX-M-14	7UON	1.35	2023-01-25	H6UQI0	36635385	10.1038/S42003-023-04422-Z	pdb	Y105W	PO4	P 32 2 1	41.430 41.430 230.641 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	7ZPV	1.40	2022-11-16	D2D9A0			pdb		SO4	P 32 2 1	42.160 42.160 234.350 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8AF7	1.55	2022-11-16	D2D9A0			pdb		SO4	P 32 2 1	42.160 42.160 234.350 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8AF8	1.55	2022-11-16	Q7BGE9			pdb		SO4	P 32 2 1	42.160 42.160 234.350 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8B2O	1.86	2023-05-24	D2D9A0	37185266	10.1038/S41467-023-37834-W	pdb	E166A	*AIX	P 32 2 1	41.812 41.812 232.962 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8B2V	1.73	2023-05-24	D2D9A0	37185266	10.1038/S41467-023-37834-W	pdb	E166A	*AIX	P 32 2 1	41.877 41.877 232.904 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8B2W	1.78	2023-05-24	D2D9A0	37185266	10.1038/S41467-023-37834-W	pdb	E166A	*AIX	P 32 2 1	41.812 41.812 232.864 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8B3M	1.97	2023-05-24	D2D9A0	37185266	10.1038/S41467-023-37834-W	pdb		*NXL	P 32 2 1	41.850 41.850 232.850 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8DOD	1.61	2023-04-05	H6UQI0	36963495	10.1016/J.JBC.2023.104630	pdb	S130A	K PCA	P 32 2 1	41.490 41.490 230.780 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8DOE	1.50	2023-04-05	H6UQI0	36963495	10.1016/J.JBC.2023.104630	pdb	N106A		P 1 21 1	49.840 37.910 65.460 ♦ 90.00 103.44 90.00	2
A	CTX-M-14	8DON	1.36	2023-04-05	H6UQI0	36963495	10.1016/J.JBC.2023.104630	pdb	T215A	PO4	P 32 2 1	41.430 41.430 231.260 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8DP4	1.40	2023-04-05	H6UQI0	36963495	10.1016/J.JBC.2023.104630	pdb	T235A Y129F	PCA	P 41 21 2	41.960 41.960 260.527 ♦ 90.00 90.00 90.00	8
A	CTX-M-14	8DPQ	1.67	2023-04-05	H6UQI0	36963495	10.1016/J.JBC.2023.104630	pdb	N170A	EDO	P 32 2 1	41.418 41.418 230.493 ♦ 90.00 90.00 120.00	6
A	CTX-M-14	8ELA	1.50	2023-04-05	Q9L5C7	36963495	10.1016/J.JBC.2023.104630	pdb	N132A	CL MES SO4 ZN	C 2 2 21	59.314 60.430 264.216 ♦ 90.00 90.00 90.00	16
A	CTX-M-14	8ELB	1.50	2023-04-05	Q9L5C7	36963495	10.1016/J.JBC.2023.104630	pdb	N132A	PEG	C 2 2 21	59.230 60.410 264.100 ♦ 90.00 90.00 90.00	16

Structures