Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Structures

Ambler
class
Protein
name
PDB
code
Resolution
(Å)
Release
date
UniProt
code
PubMed
ID
DOI
PDB
Mutations
Ligands
Space
group
Unit cell parameters
Z
value
ABlaC2GDN1.722006-04-18P9WKD3 1687077010.1128/AAC.00320-06pdb P 21 21 2142.744 71.283 85.169 ♦ 90.00 90.00 90.004
ABlaC3CG51.702008-05-27P9WKD3 1842234210.1021/BI8001055pdb *ISS PO4 P 21 21 2149.666 67.655 75.032 ♦ 90.00 90.00 90.004
ABlaC3DWZ1.802009-03-10P9WKD3 1925163010.1126/SCIENCE.1167498pdb *DWZ PO4 P 21 21 2149.852 67.595 75.188 ♦ 90.00 90.00 90.004
ABlaC3IQA2.202010-04-14P9WKD3 2035317510.1021/BI100232Qpdb *DRW PO4 P 21 21 2149.989 68.068 75.792 ♦ 90.00 90.00 90.004
ABlaC3M6B1.302010-04-14P9WKD3 2035317510.1021/BI100232Qpdb *1RG PO4 P 21 21 2149.657 67.922 75.546 ♦ 90.00 90.00 90.004
ABlaC3M6H1.992010-04-14P9WKD3 2035317510.1021/BI100232Qpdb *2RG PO4 P 21 21 2149.934 67.830 75.201 ♦ 90.00 90.00 90.004
ABlaC3N6I2.002011-12-14P9WKD3 pdbE182A *XD1 PO4 P 21 21 2149.855 68.052 75.469 ♦ 90.00 90.00 90.004
ABlaC3N7W1.702011-12-14P9WKD3 pdbE182A *AXL PO4 P 21 21 2149.855 68.150 75.586 ♦ 90.00 90.00 90.004
ABlaC3N8L1.402011-12-14P9WKD3 pdbE182A *AIX PO4 P 21 21 2149.703 67.836 75.245 ♦ 90.00 90.00 90.004
ABlaC3N8R1.412011-12-14P9WKD3 pdbE182A *CB9 PO4 P 21 21 2149.631 67.856 75.390 ♦ 90.00 90.00 90.004
ABlaC3N8S2.002010-11-24P9WKD3 2096111210.1021/BI1015088pdbE182A *XD2 PO4 P 21 21 2149.831 67.869 75.314 ♦ 90.00 90.00 90.004
ABlaC3NBL2.002011-12-14P9WKD3 pdbE182A *DXF P 21 21 2149.383 68.102 75.652 ♦ 90.00 90.00 90.004
ABlaC3NC81.502011-12-14P9WKD3 pdbE182A *DH4 PO4 P 21 21 2149.809 67.947 75.279 ♦ 90.00 90.00 90.004
ABlaC3NCK2.802011-12-14P9WKD3 pdbE182A *NFF P 21 21 2148.671 67.822 76.643 ♦ 90.00 90.00 90.004
ABlaC3NDE1.702011-12-14P9WKD3 pdbE182A *9EP PO4 P 21 21 2149.821 67.837 75.323 ♦ 90.00 90.00 90.004
ABlaC3NDG1.902011-12-14P9WKD3 pdbE182A *7EP PO4 P 21 21 2149.355 67.908 75.569 ♦ 90.00 90.00 90.004
ABlaC3NY41.222010-11-24P9WKD3 2096111210.1021/BI1015088pdbK87A $SMX PO4 P 21 21 2149.804 67.915 75.524 ♦ 90.00 90.00 90.004
ABlaC3VFF2.782012-09-19P9WKD3 pdbE166A *CD8 PO4 P 1 21 180.061 96.603 108.555 ♦ 90.00 107.69 90.008
ABlaC3VFH2.572012-09-19P9WKD3 pdbE166A *CD6 PO4 P 1 21 179.396 97.459 110.958 ♦ 90.00 108.37 90.008
ABlaC3ZHH2.852013-09-25P9WKD3 2402382110.1371/JOURNAL.PONE.0073123pdb SO4 P 1 21 178.737 96.438 111.005 ♦ 90.00 108.48 90.008
ABlaC4DF62.292012-07-18P9WKD3 2258768810.1021/BI300508Rpdb *NXL PO4 P 21 21 2149.960 68.004 75.705 ♦ 90.00 90.00 90.004
ABlaC4EBL2.102013-04-03P9WKD3 pdbE166A *SFR PO4 P 1 21 178.792 96.946 109.526 ♦ 90.00 107.95 90.008
ABlaC4EBN2.852013-04-03P9WKD3 pdbE166A *AXL PO4 P 1 21 179.567 96.672 109.808 ♦ 90.00 107.52 90.008
ABlaC4EBP2.292013-04-03P9WKD3 pdbE166A *PCZ PO4 P 1 21 178.820 96.152 107.088 ♦ 90.00 106.34 90.008
ABlaC4JLF2.102013-10-30P9WKD3 pdbR236A PO4 P 21 21 2149.410 67.427 74.634 ♦ 90.00 90.00 90.004
ABlaC4Q8I1.902014-08-20P9WKD3 2484640910.1021/bi500339jpdb *TEB PO4 P 21 21 2149.925 68.026 75.554 ♦ 90.00 90.00 90.004
ABlaC4QB81.762014-08-20P9WKD3 2484640910.1021/bi500339jpdbK87A $1TE PO4 P 21 21 2149.569 67.558 75.105 ♦ 90.00 90.00 90.004
ABlaC4QHC1.902015-07-22P9WKD3 2623711810.1021/acs.biochem.5b00698pdb *33V PO4 P 21 21 2149.699 68.330 75.247 ♦ 90.00 90.00 90.004
ABlaC4X6T1.402015-12-23P9WKD3 10.1021/ACSINFECDIS.5B00003pdb *3Y6 PO4 P 21 21 2143.264 71.417 84.683 ♦ 90.00 90.00 90.004
ABlaC5NJ21.192017-11-15A0A0T9EA39 2908769610.1021/ACS.BIOCHEM.7B00556pdb ACT AE4 ETE PO4 P 139.591 41.683 76.841 ♦ 101.28 90.11 90.432
ABlaC5OYO2.102017-11-15A0A0T9EA39 2908769610.1021/ACS.BIOCHEM.7B00556pdb ACT GOL PGE P 139.589 41.417 76.523 ♦ 104.29 90.07 90.672
ABlaC6B5X2.452018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb PO4 P 1 21 179.040 97.190 110.620 ♦ 90.00 108.71 90.008
ABlaC6B5Y2.752018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 PO4 P 1 21 178.530 96.030 112.580 ♦ 90.00 109.68 90.008
ABlaC6B682.152018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 *FZS PO4 P 1 21 178.700 96.030 113.060 ♦ 90.00 109.87 90.008
ABlaC6B692.202018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 *CUG *FZS PO4 P 1 21 178.860 96.310 113.560 ♦ 90.00 109.98 90.008
ABlaC6B6A2.302018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 *FZS PO4 P 1 21 177.850 95.310 111.870 ♦ 90.00 109.82 90.008
ABlaC6B6B1.802018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb P 1 21 139.600 41.600 69.310 ♦ 90.00 104.82 90.002
ABlaC6B6C1.902018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 P 1 21 139.530 41.590 69.360 ♦ 90.00 104.81 90.002
ABlaC6B6D1.802018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 *FZS P 1 21 139.630 41.650 69.350 ♦ 90.00 104.93 90.002
ABlaC6B6E1.902018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 *FZS P 1 21 139.640 41.740 69.520 ♦ 90.00 104.94 90.002
ABlaC6B6F2.052018-06-27P9WKD3 2984835810.1186/S12915-018-0524-5pdb $9F2 P 1 21 139.730 41.690 69.530 ♦ 90.00 104.68 90.002
ABlaC6H271.632019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdbS70C EDO PG0 P 1 21 139.600 76.410 79.320 ♦ 90.00 90.70 90.004
ABlaC6H281.192019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdb 15P GOL PEG P 139.590 41.700 76.760 ♦ 101.31 90.02 90.052
ABlaC6H2A2.542019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdb DTT GOL PO4 TAM P 43 21 2108.864 108.864 260.577 ♦ 90.00 90.00 90.0024
ABlaC6H2C1.932019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdb *ISS 15P ACT CO2 GOL P 139.650 41.980 76.917 ♦ 78.40 89.95 89.752
ABlaC6H2G2.802019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdb *FK2 ACT P 139.398 41.314 76.222 ♦ 75.67 89.96 89.262
ABlaC6H2H1.622019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdb *NXL 15P P 139.520 41.324 76.360 ♦ 104.83 90.03 91.182
ABlaC6H2I2.722019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdb *TBE ACT P 139.632 41.523 76.417 ♦ 103.83 89.99 90.792
ABlaC6H2K1.902019-01-23P0A5I7 3063273910.1021/ACS.BIOCHEM.8B01085pdb *TSL ACT GOL PEG P 139.710 41.950 76.930 ♦ 105.10 89.95 90.812
ABlaC6N141.522019-08-28A0A0T9EA39 3126965610.3390/IJMS20133247pdb PO4 SEP P 21 21 2149.840 68.037 75.454 ♦ 90.00 90.00 90.004
ABlaC7A741.602021-05-19P9WKD3 3403104910.1128/AAC.02628-20pdbG132N CSD EDO GOL NA PO4 P 21 21 2154.007 54.596 79.398 ♦ 90.00 90.00 90.004
Legend for ligands: * Ligand covalently-bound to active site residues; $ Non-covalent ligand (Michaelis complex); # Ligand coordinated to active site metal ions.

Statistics (number of structures): Overall (1429); class A (543); subclass B1 (348); subclass B2 (15); subclass B3 (82); class C (221); class D (220).

Last updated: November 06, 2021.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu