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Ambler class |
Protein name |
PDB code |
Resolution (Å) |
Release date |
UniProt code |
PubMed ID |
DOI |
PDB |
Mutations |
Ligands |
Space group |
Unit cell parameters |
Z value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ▲ ▼ | ▲ ▼ | ▲ ▼ | ▲ ▼ | ▲ ▼ | ▲ ▼ | ||||||||
| A | BlaC | 2GDN | 1.72 | 2006-04-18 | P9WKD3 | 16870770 | 10.1128/AAC.00320-06 | pdb | P 21 21 21 | 42.744 71.283 85.169 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3CG5 | 1.70 | 2008-05-27 | P9WKD3 | 18422342 | 10.1021/BI8001055 | pdb | *ISS PO4 | P 21 21 21 | 49.666 67.655 75.032 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 3DWZ | 1.80 | 2009-03-10 | P9WKD3 | 19251630 | 10.1126/SCIENCE.1167498 | pdb | *DWZ PO4 | P 21 21 21 | 49.852 67.595 75.188 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 3IQA | 2.20 | 2010-04-14 | P9WKD3 | 20353175 | 10.1021/BI100232Q | pdb | *DRW PO4 | P 21 21 21 | 49.989 68.068 75.792 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 3M6B | 1.30 | 2010-04-14 | P9WKD3 | 20353175 | 10.1021/BI100232Q | pdb | *1RG PO4 | P 21 21 21 | 49.657 67.922 75.546 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 3M6H | 1.99 | 2010-04-14 | P9WKD3 | 20353175 | 10.1021/BI100232Q | pdb | *2RG PO4 | P 21 21 21 | 49.934 67.830 75.201 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 3N6I | 2.00 | 2011-12-14 | P9WKD3 | pdb | E182A | *XD1 PO4 | P 21 21 21 | 49.855 68.052 75.469 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3N7W | 1.70 | 2011-12-14 | P9WKD3 | pdb | E182A | *AXL PO4 | P 21 21 21 | 49.855 68.150 75.586 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3N8L | 1.40 | 2011-12-14 | P9WKD3 | pdb | E182A | *AIX PO4 | P 21 21 21 | 49.703 67.836 75.245 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3N8R | 1.41 | 2011-12-14 | P9WKD3 | pdb | E182A | *CB9 PO4 | P 21 21 21 | 49.631 67.856 75.390 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3N8S | 2.00 | 2010-11-24 | P9WKD3 | 20961112 | 10.1021/BI1015088 | pdb | E182A | *XD2 PO4 | P 21 21 21 | 49.831 67.869 75.314 ♦ 90.00 90.00 90.00 | 4 |
| A | BlaC | 3NBL | 2.00 | 2011-12-14 | P9WKD3 | pdb | E182A | *DXF | P 21 21 21 | 49.383 68.102 75.652 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3NC8 | 1.50 | 2011-12-14 | P9WKD3 | pdb | E182A | *DH4 PO4 | P 21 21 21 | 49.809 67.947 75.279 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3NCK | 2.80 | 2011-12-14 | P9WKD3 | pdb | E182A | *NFF | P 21 21 21 | 48.671 67.822 76.643 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3NDE | 1.70 | 2011-12-14 | P9WKD3 | pdb | E182A | *9EP PO4 | P 21 21 21 | 49.821 67.837 75.323 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3NDG | 1.90 | 2011-12-14 | P9WKD3 | pdb | E182A | *7EP PO4 | P 21 21 21 | 49.355 67.908 75.569 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 3NY4 | 1.22 | 2010-11-24 | P9WKD3 | 20961112 | 10.1021/BI1015088 | pdb | K87A | $SMX PO4 | P 21 21 21 | 49.804 67.915 75.524 ♦ 90.00 90.00 90.00 | 4 |
| A | BlaC | 3VFF | 2.78 | 2012-09-19 | P9WKD3 | pdb | E166A | *CD8 PO4 | P 1 21 1 | 80.061 96.603 108.555 ♦ 90.00 107.69 90.00 | 8 | ||
| A | BlaC | 3VFH | 2.57 | 2012-09-19 | P9WKD3 | pdb | E166A | *CD6 PO4 | P 1 21 1 | 79.396 97.459 110.958 ♦ 90.00 108.37 90.00 | 8 | ||
| A | BlaC | 3ZHH | 2.85 | 2013-09-25 | P9WKD3 | 24023821 | 10.1371/JOURNAL.PONE.0073123 | pdb | SO4 | P 1 21 1 | 78.737 96.438 111.005 ♦ 90.00 108.48 90.00 | 8 | |
| A | BlaC | 4DF6 | 2.29 | 2012-07-18 | P9WKD3 | 22587688 | 10.1021/BI300508R | pdb | *NXL PO4 | P 21 21 21 | 49.960 68.004 75.705 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 4EBL | 2.10 | 2013-04-03 | P9WKD3 | pdb | E166A | *SFR PO4 | P 1 21 1 | 78.792 96.946 109.526 ♦ 90.00 107.95 90.00 | 8 | ||
| A | BlaC | 4EBN | 2.85 | 2013-04-03 | P9WKD3 | pdb | E166A | *AXL PO4 | P 1 21 1 | 79.567 96.672 109.808 ♦ 90.00 107.52 90.00 | 8 | ||
| A | BlaC | 4EBP | 2.29 | 2013-04-03 | P9WKD3 | pdb | E166A | *PCZ PO4 | P 1 21 1 | 78.820 96.152 107.088 ♦ 90.00 106.34 90.00 | 8 | ||
| A | BlaC | 4JLF | 2.10 | 2013-10-30 | P9WKD3 | pdb | R236A | PO4 | P 21 21 21 | 49.410 67.427 74.634 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 4Q8I | 1.90 | 2014-08-20 | P9WKD3 | 24846409 | 10.1021/bi500339j | pdb | *TEB PO4 | P 21 21 21 | 49.925 68.026 75.554 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 4QB8 | 1.76 | 2014-08-20 | P9WKD3 | 24846409 | 10.1021/bi500339j | pdb | K87A | $1TE PO4 | P 21 21 21 | 49.569 67.558 75.105 ♦ 90.00 90.00 90.00 | 4 |
| A | BlaC | 4QHC | 1.90 | 2015-07-22 | P9WKD3 | 26237118 | 10.1021/acs.biochem.5b00698 | pdb | *33V PO4 | P 21 21 21 | 49.699 68.330 75.247 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 4X6T | 1.40 | 2015-12-23 | P9WKD3 | 10.1021/ACSINFECDIS.5B00003 | pdb | *3Y6 PO4 | P 21 21 21 | 43.264 71.417 84.683 ♦ 90.00 90.00 90.00 | 4 | ||
| A | BlaC | 5NJ2 | 1.19 | 2017-11-15 | A0A0T9EA39 | 29087696 | 10.1021/ACS.BIOCHEM.7B00556 | pdb | ACT AE4 ETE PO4 | P 1 | 39.591 41.683 76.841 ♦ 101.28 90.11 90.43 | 2 | |
| A | BlaC | 5OYO | 2.10 | 2017-11-15 | A0A0T9EA39 | 29087696 | 10.1021/ACS.BIOCHEM.7B00556 | pdb | ACT GOL PGE | P 1 | 39.589 41.417 76.523 ♦ 104.29 90.07 90.67 | 2 | |
| A | BlaC | 6B5X | 2.45 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | PO4 | P 1 21 1 | 79.040 97.190 110.620 ♦ 90.00 108.71 90.00 | 8 | |
| A | BlaC | 6B5Y | 2.75 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 PO4 | P 1 21 1 | 78.530 96.030 112.580 ♦ 90.00 109.68 90.00 | 8 | |
| A | BlaC | 6B68 | 2.15 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 *FZS PO4 | P 1 21 1 | 78.700 96.030 113.060 ♦ 90.00 109.87 90.00 | 8 | |
| A | BlaC | 6B69 | 2.20 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 *CUG *FZS PO4 | P 1 21 1 | 78.860 96.310 113.560 ♦ 90.00 109.98 90.00 | 8 | |
| A | BlaC | 6B6A | 2.30 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 *FZS PO4 | P 1 21 1 | 77.850 95.310 111.870 ♦ 90.00 109.82 90.00 | 8 | |
| A | BlaC | 6B6B | 1.80 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | P 1 21 1 | 39.600 41.600 69.310 ♦ 90.00 104.82 90.00 | 2 | ||
| A | BlaC | 6B6C | 1.90 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 | P 1 21 1 | 39.530 41.590 69.360 ♦ 90.00 104.81 90.00 | 2 | |
| A | BlaC | 6B6D | 1.80 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 *FZS | P 1 21 1 | 39.630 41.650 69.350 ♦ 90.00 104.93 90.00 | 2 | |
| A | BlaC | 6B6E | 1.90 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 *FZS | P 1 21 1 | 39.640 41.740 69.520 ♦ 90.00 104.94 90.00 | 2 | |
| A | BlaC | 6B6F | 2.05 | 2018-06-27 | P9WKD3 | 29848358 | 10.1186/S12915-018-0524-5 | pdb | $9F2 | P 1 21 1 | 39.730 41.690 69.530 ♦ 90.00 104.68 90.00 | 2 | |
| A | BlaC | 6H27 | 1.63 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | S70C | EDO PG0 | P 1 21 1 | 39.600 76.410 79.320 ♦ 90.00 90.70 90.00 | 4 |
| A | BlaC | 6H28 | 1.19 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | 15P GOL PEG | P 1 | 39.590 41.700 76.760 ♦ 101.31 90.02 90.05 | 2 | |
| A | BlaC | 6H2A | 2.54 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | DTT GOL PO4 TAM | P 43 21 2 | 108.864 108.864 260.577 ♦ 90.00 90.00 90.00 | 24 | |
| A | BlaC | 6H2C | 1.93 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | *ISS 15P ACT CO2 GOL | P 1 | 39.650 41.980 76.917 ♦ 78.40 89.95 89.75 | 2 | |
| A | BlaC | 6H2G | 2.80 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | *FK2 ACT | P 1 | 39.398 41.314 76.222 ♦ 75.67 89.96 89.26 | 2 | |
| A | BlaC | 6H2H | 1.62 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | *NXL 15P | P 1 | 39.520 41.324 76.360 ♦ 104.83 90.03 91.18 | 2 | |
| A | BlaC | 6H2I | 2.72 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | *TBE ACT | P 1 | 39.632 41.523 76.417 ♦ 103.83 89.99 90.79 | 2 | |
| A | BlaC | 6H2K | 1.90 | 2019-01-23 | P0A5I7 | 30632739 | 10.1021/ACS.BIOCHEM.8B01085 | pdb | *TSL ACT GOL PEG | P 1 | 39.710 41.950 76.930 ♦ 105.10 89.95 90.81 | 2 | |
| A | BlaC | 6N14 | 1.52 | 2019-08-28 | A0A0T9EA39 | 31269656 | 10.3390/IJMS20133247 | pdb | PO4 SEP | P 21 21 21 | 49.840 68.037 75.454 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 7A74 | 1.60 | 2021-05-19 | P9WKD3 | 34031049 | 10.1128/AAC.02628-20 | pdb | G132N | CSD EDO GOL NA PO4 | P 21 21 21 | 54.007 54.596 79.398 ♦ 90.00 90.00 90.00 | 4 |
| A | BlaC | 8BTU | 1.80 | 2023-07-05 | P9WKD2 | 37335937 | 10.1111/FEBS.16892 | pdb | D179N | P 1 21 1 | 38.370 54.050 53.640 ♦ 90.00 93.20 90.00 | 2 | |
| A | BlaC | 8BTV | 1.95 | 2023-07-05 | P9WKD2 | 37335937 | 10.1111/FEBS.16892 | pdb | D179N | *TSL GOL PO4 | P 1 21 1 | 38.945 54.727 53.879 ♦ 90.00 92.86 90.00 | 2 |
| A | BlaC | 8BTW | 1.90 | 2023-07-05 | P9WKD2 | 37335937 | 10.1111/FEBS.16892 | pdb | D179N | *4D6 GOL NA PO4 | P 21 21 21 | 53.819 54.452 79.517 ♦ 90.00 90.00 90.00 | 4 |
| A | BlaC | 8BV4 | 1.95 | 2023-07-05 | A5U493 | 37335937 | 10.1111/FEBS.16892 | pdb | *4D6 GOL PO4 | P 21 21 21 | 53.490 54.656 78.109 ♦ 90.00 90.00 90.00 | 4 | |
| A | BlaC | 8GCS | 2.62 | 2023-09-20 | P0A5I7 | 37679343 | 10.1038/S41467-023-41246-1 | pdb | PO4 | P 1 21 1 | 80.500 98.790 111.470 ♦ 90.00 108.48 90.00 | 8 | |
| A | BlaC | 8GCT | 2.75 | 2023-09-20 | P0A5I7 | 37679343 | 10.1038/S41467-023-41246-1 | pdb | PO4 | P 1 21 1 | 80.440 98.810 112.010 ♦ 90.00 108.67 90.00 | 8 | |
| A | BlaC | 8GCV | 2.20 | 2023-09-20 | P0A5I7 | 37679343 | 10.1038/S41467-023-41246-1 | pdb | PO4 | P 1 21 1 | 79.640 98.090 110.880 ♦ 90.00 108.45 90.00 | 8 | |
| A | BlaC | 8GCX | 3.20 | 2023-09-20 | P0A5I7 | 37679343 | 10.1038/S41467-023-41246-1 | pdb | *TSL PO4 | P 1 21 1 | 80.140 98.070 113.720 ♦ 90.00 109.36 90.00 | 8 | |
| A | BlaC | 8OE1 | 1.90 | 2023-08-23 | A0A655AHQ9 | 37549761 | 10.1016/J.IJBIOMAC.2023.126160 | pdb | GOL | P 1 | 40.600 54.178 56.036 ♦ 90.18 111.10 91.78 | 2 | |
| A | BlaC | 8OE5 | 1.80 | 2023-08-23 | A0A655AHQ9 | 37549761 | 10.1016/J.IJBIOMAC.2023.126160 | pdb | FLC GOL | P 1 | 40.627 53.693 56.273 ♦ 88.19 69.58 87.73 | 2 |
Statistics (number of structures): Overall (1663); class A (626); subclass B1 (403); subclass B2 (16); subclass B3 (104); class C (246); class D (268).
Last updated: November 20, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu