Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Synthetic Mutants (work in progress)

Ambler class
Protein name
Mutations
PubMed ID
DOI
PDB structures
Hydrolytic profile
APC1-1A238S I239DEL 886964010.1093/PROTEIN/8.12.1275
APC1-1N170D E166Q 1043608310.1093/PROTEIN/12.7.573
APC1-1N170Q 898798010.1021/BI962242Aview
APC1-1N170M 898798010.1021/BI962242Aview
APC1-1D179N 189284910.1021/BI00103A017view
APC1-1E166D N170Q 1132785510.1021/BI002277H
APC1-1K73H 882315810.1021/BI961153Vview
APC1-1S70A 882315810.1021/BI961153Vview

Statistics (number of mutants): Overall (167); class A (91); subclass B1 (35); subclass B2 (3); subclass B3 (6); class C (19); class D (13).

Last updated: November 06, 2021.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu